Results 121 to 130 of about 39,175 (290)

Advances in the molecular regulation mechanism of tumor dormancy and its therapeutic strategy

open access: yesDiscover Oncology
Tumor dormancy is a stage in the growth and development of malignant cells and is one of the biological characteristics of malignant cells. Complex transitions involving dormant tumor cells between quiescent and proliferative states pose challenges for ...
Yuan Wang   +7 more
doaj   +1 more source

To Tell or Not to Tell? On the Under Communicating of Sustainability in Digital Environments

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The paper investigates sustainability communication using digital tools—such as social media, websites, emails, and newsletters—and delves into the drivers that determine the undercommunication of sustainability (i.e., the green blushing phenomenon) in digital environments.
Simone Guercini   +3 more
wiley   +1 more source

Biopharmaceutics [PDF]

open access: yes, 2012
久保 義行   +3 more
core   +2 more sources

Hands‐free from inoculation to harvest: Microbial fermentation with multivariate model to automate induction of recombinant protein expression

open access: yesBiotechnology Progress, EarlyView.
Abstract Industrial fermentation continually improves biological process control for a wide range of microorganisms used in multi‐billion‐dollar industries including industrial enzymes, pharmaceuticals, foods, beverages, commodity chemicals, and bioenergy.
Jennifer Reid   +6 more
wiley   +1 more source

Harvesting AAV by tangential flow filtration using reverse asymmetric membranes

open access: yesBiotechnology Progress, EarlyView.
Abstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Xiaolei Hao   +5 more
wiley   +1 more source

In vitro Performance Assessment of Recent Nebuliser Delivery Systems for Nebulisation of Approved Aerosolised Tobramycin (TOBI)® [PDF]

open access: yes, 2015
YesTOBI® is a recently marketed preservative and sulphate free tobramycin formulation approved by FDA for maintenance therapy for patient with cystic fibrosis.
Assi, Khaled H.   +3 more
core  

Enhancing rapid Protein A performance in monoclonal antibody processing: Anion exchange chromatographic clarification

open access: yesBiotechnology Progress, EarlyView.
Abstract Clarification fidelity, including reduction of insoluble and soluble contaminants, has been demonstrated to significantly affect the performance and robustness of the Protein A capture chromatography step during the purification of monoclonal antibodies (mAb) and their derivatives expressed in CHO cell cultures.
Andrew Vail   +3 more
wiley   +1 more source

Optimizing clarification processes in biopharmaceutical manufacturing through quality by design: Strategies, implications, and future prospects

open access: yesBiotechnology Progress, EarlyView.
Abstract Biopharmaceutical manufacturing processes in which the product of interest is extracellularly expressed typically employ a clarification step following cell culture or fermentation. During clarification, crude cell culture fluid or fermentation broth is processed to remove insoluble solids, cells, debris, and other particulates, with the ...
Kyeong‐won Yeop   +7 more
wiley   +1 more source

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