Results 271 to 280 of about 39,175 (290)

Decoding the Genome of the Komagataella phaffii Type Strain CBS 2612

open access: yesYeast, EarlyView.
Visualization of annotated features in the genome of the Komagataella phaffii type strain CBS 2612 including four SNPs and centromere positions. Comparison of the number of coding sequences, tRNAs and rRNAs to other closely related K. phaffii strains.
Nadine Elpida Tatto   +6 more
wiley   +1 more source

Endogenous Technology Spillovers in R&D Collaboration Networks

open access: yesThe RAND Journal of Economics, EarlyView.
ABSTRACT We introduce an R&D network formation model where firms choose both R&D efforts and collaboration partners. Neighbors in the network benefit from each other's R&D through technology spillovers, and there exists competition effects reflecting strategic substitutability in R&D.
Chih‐Sheng Hsieh   +2 more
wiley   +1 more source

Baricitinib Augments Lonafarnib Therapy to Preserve Colonic Homeostasis and Microbial Balance in a Mouse Model of Progeria

open access: yesAging Cell, EarlyView.
Combined baricitinib and lonafarnib treatment improved colonic pathology in LmnaG609G/G609G progeria mice by reducing progerin, maintaining epithelial regeneration, mitigating inflammation and senescence, and preserving microbiome composition. ABSTRACT Hutchinson‐Gilford Progeria Syndrome (HGPS) is a fatal genetic disorder caused by progerin, a mutant ...
Moritz Schroll   +4 more
wiley   +1 more source

Criteria for Commencing and Continuing Subsidised Janus Kinase Inhibitor Therapy in Australian Alopecia Areata Patients—Results From an Australian Expert Consensus Exercise

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Background/Objectives Janus kinase inhibitors (JAKis) have been approved by the Therapeutic Goods Administration for severe alopecia areata (AA) in Australia. However, access is limited as JAKis are not currently subsidised on the Pharmaceutical Benefits Scheme for this indication. This study aimed to establish expert consensus on criteria for
Meryl Thomas   +23 more
wiley   +1 more source

Distinct Roles for Thymic Stromal Lymphopoietin (TSLP) and IL‐33 in Experimental Eosinophilic Esophagitis

open access: yesAllergy, EarlyView.
This study described the expression and function of TSLP and IL‐33 in an experimental model of EoE. TSLP and IL‐33 were overexpressed in human and experimental EoE. Human and mouse esophageal MCs displayed the highest level of Crlf2 (TSLPR) compared to other immune cells.
Anish Dsilva   +16 more
wiley   +1 more source

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