Results 161 to 170 of about 1,099,223 (288)

Physics of Protein Aggregation in Normal and Accelerated Brain Aging

open access: yesBioEssays, EarlyView.
Soluble monomeric proteins precipitate via nucleation into insoluble amyloids in response to age‐related exposures (e.g., microbes, nanoparticles). Persistent soluble‐to‐insoluble phase transition depletes the functional proteins. In normal aging, replacement matches loss; in accelerated aging, it does not.
Alberto J. Espay   +9 more
wiley   +1 more source

Synphilin-1 regulates mechanotransduction in rigidity sensing through interaction with zyxin. [PDF]

open access: yesJ Nanobiotechnology
Kim SG   +9 more
europepmc   +1 more source

Memory Gate Controlled by Contexts: Potential Key Structure That Could Link Small Associative Failures With Severe Cognitive Disorders

open access: yesBioEssays, EarlyView.
Memory gate (MG) hypothesis assumes a neural structure that connects inputs to appropriate contexts. Panel A shows an input (green) that, in the MG, does not match the context (red): memory does not recognize it. Panel B shows that, in the MG, the context (green) matches the input: memory recognizes the pattern.
Eduardo Mizraji, Juan Lin, Andrés Pomi
wiley   +1 more source

Transferrin Purification, Biophysical Characterization, and Lung Biodistribution in Sickle Cell Disease Mice

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Plasma transferrin (Tf) is the transport protein central to the process of iron recycling and metabolism. Holo‐Tf serves as the body's pool of ferric iron, facilitating transport from tissues such as the intestine, liver, spleen, and finally bone marrow, where iron is incorporated into erythropoiesis.
Shuwei Lu   +9 more
wiley   +1 more source

Toward universal models for collective interactions in biomolecular condensates. [PDF]

open access: yesBiophys Rev (Melville)
Milanetti E   +4 more
europepmc   +1 more source

Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials

open access: yesBMEMat, EarlyView.
Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang   +9 more
wiley   +1 more source

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