We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang +7 more
wiley +1 more source
Dense tactile streams from across the humanoid body converge on collide in a central wiring and data bottleneck. By relocating computation closer to and then into the skin itself, near‐ and in‐sensor architectures, together with neuromorphic computing, chart a path toward perception‐native electronic skin, in which the conversion of stimulus into ...
Mijin Kim +6 more
wiley +1 more source
Auditory–Tactile Congruence for Synthesis of Adaptive Pain Expressions in RoboPatients
In this work, we explore auditory–tactile congruence for synthesizing adaptive vocal pain expressions in robopatients. Using a robopatient platform that integrates vocal pain sounds with palpation forces, we conducted 7680 trials across 20 participants.
Saitarun Nadipineni +4 more
wiley +1 more source
Association Between Cervical Lordosis Restoration and Clinical Recovery Following a Motor Vehicle Collision: A Chiropractic BioPhysics Case Report With a 17-Month Follow-Up. [PDF]
Woodham TJ +4 more
europepmc +1 more source
From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley +1 more source
Correction: Peroxiredoxins in the Developmental Origins of Health and Disease: Insights from Maternal Under and Overnutrition - A Critical Interpretative Scoping Review. [PDF]
Fioretto MN +6 more
europepmc +1 more source
Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu +7 more
wiley +1 more source
Correction: GerAB residues predicted to interact with water based on MD simulations mediate germinosome stability in <i>Bacillus subtilis</i> spores. [PDF]
Chen L +5 more
europepmc +1 more source
Katedra biofyziky a fyzikální chemieDepartment of Biophysics and Physical ChemistryFaculty of Pharmacy in Hradec KrálovéFarmaceutická fakulta v Hradci ...
Jelínková, Aneta
core
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng +15 more
wiley +1 more source

