Results 81 to 90 of about 441,621 (301)

Communications Biophysics [PDF]

, 1960
Contains reports on two research projects.United States Air Force (Contract AF19(604)-4112)United States Air Force, Office of Scientific Research, Air Research and Development Command (Contract AF 61 (052)-107)Rockefeller ...
Brown, J. E., III, Goldstein, M. H., Jr., Nicotra, L.   +2 more
core  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Mechanotransduction mechanisms in human erythrocytes: Fundamental physiology and clinical significance

Channels
The hallmarks of mechanosensitive ion channels have been observed for half a century in various cell lines, although their mechanisms and molecular identities remained unknown until recently. Identification of the bona fide mammalian mechanosensory Piezo
Lennart Kuck, Lars Kaestner, Stéphane Egée, Virgilio L. Lew, Michael J. Simmonds   +4 more
doaj   +1 more source

[PDF]

Cellular biophysics - ionizing radiation effect on genetics, cell mutation, and mutagenic nature of tritium ...

core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Erythrocyte Distribution by Surface Charge: Biophysical Characteristics of Heterogeneity, Diagnostic Significance and Application in Transfusionology and Biobanking

Innovative Biosystems and Bioengineering
Long-term storage of erythrocytes, a vital component of modern transfusion medicine, is accompanied by structural, metabolic, and biophysical alterations that reduce their functional activity.
Daniil Liadov, Volodymyr Berest, Tetiana Liadova, Fedir Hladkykh   +3 more
doaj   +1 more source

Organismic Supercategores: II. On Multistable Systems\ud \ud [PDF]

, 1970
The representation of biological systems in terms of organismic supercategories, introduced in previous papers by Baianu et al. (Bull. Math. Biophysics,30, 625–636;31, 59–70) is further discussed.
Baianu, Prof. Dr. I.C.
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Communications Biophysics [PDF]

, 1982
Contains reports on ten research projects.National Institutes of Health (Grant 5 P01 NS13126)National Institutes of Health (Training Grant 5 T32 NS0704)National Science Foundation (Grant BNS80-06369)National Institutes of Health (Grant 5 R01 NS11153 ...
Boduch, Raymond, Braida, Louis D., Bustamante, Diane K., Chomsky, Carol, Clements, Mark A., Coker, Jackie, DeGennaro, Steven V., Dowdy, Leonard C., Durlach, Nathaniel I., Epstein, Michael A., Farrar, Catherine L., Florentine, Mary S., Freeman, Dennis M., Frishkopf, Lawrence S., Garrett, Merrill F., Houtsma, Adrian J. M., Kiang, Nelson Y-S., Milner, Paul, Moser, James, Oman, Charles M., Peake, William T., Perkell, Joseph S., Peterson, Patrick M., Picheny, Michael A., Rabinowitz, William M., Reed, Charlotte M., Reid, Jean P., Rohlicek, Robin, Schultz, Martin C., Siebert, William M., Skarda, Gregory M., Uchanski, Rosalie M., Weiss, Thomas F., Widin, Gregory P., Willchur, Edgar, Zue, Victor W., Zurek, Patrick M.   +36 more
core  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source