Cell-in-Bead-in-Droplet Platform for pH-Based Microfluidic Screening of Ureolytic Bacteria. [PDF]
Efficient high‐throughput microbial screening in droplet microfluidics is often challenged by chemical crosstalk between droplets. This is particularly difficult in pH‐changing biological processes, for which more effective biochemical assays are needed.
Giovanoli D +8 more
europepmc +2 more sources
Antifungal Activity and Possible Mechanism of Action of the Zn (II) Complex With a Schiff Base Against Fluconazole-Resistant Strains of Candida spp. and Cryptococcus neoformans. [PDF]
Addressing the global challenge of antifungal resistance, this work presents a vanillin‐derived Schiff base complexed with zinc (II) (SBZ) with potent activity against fluconazole‐resistant Candida spp. and Cryptococcus neoformans. By activating an apoptotic pathway, ranging from mitochondrial depolarization and oxidative stress to fungal DNA ...
Sá LGDAV +14 more
europepmc +2 more sources
Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants. [PDF]
The study workflow utilized validated in silico [molecular docking, fingerprinting, pharmacokinetics prediction, molecular dynamics (MD) simulation, ligand‐protein contact maps] tools to bioprospect a wide variety of metabolites surveyed from South African plants with antimicrobial activities, and target them against the key S.
Aruwa CE, Sabiu S.
europepmc +2 more sources
Bioprospecting Microbial Consortia for Tebuthiuron Degradation in Agricultural Soils: An Alternative Bayesian-Driven Colorimetric Protocol. [PDF]
Microbial consortia from sugarcane soils, particularly ratoon cane environments, showed tebuthiuron‐degrading potential. Bayesian factor estimation of kernel density curves based on logarithmic response ratios enabled interpretation of non‐sigmoidal spectrophotometric data, revealing native microbiota's bioremediation capacity and offering a novel ...
Jorososki LB +4 more
europepmc +2 more sources
Polyphasic Characterization of Acetobacter indonesiensis UNPADCC 01-5 Isolated From a Traditional Fermented Food, Oncom Merah. [PDF]
The polyphasic approach (morphology, physiology, biochemistry and genetics) was used to characterize Acetobacter indonesiensis strain UNPADCC 01‐5, which was isolated from oncom merah. The strain's potential as a culture for acidic fermentations and a biofunctional agent was supported by its adaptive characteristics, which included acid tolerance ...
Syaputri Y +9 more
europepmc +2 more sources
Eksplorasi Kebutuhan Bahan Ajar pada Matakuliah Bioprospeksi
: This study aims to determine the necessity of teaching materials in Bioprospection subject. This type of descriptive qualitative research with observation, questionnaire and test data collection techniques.
Nelda Anasthasia Serena +2 more
doaj +3 more sources
Cephalotoxins: A Hotspot for Marine Bioprospecting?
Molluscs provided one of the pioneering approved pharmaceuticals from the seas: the painkiller ziconotide, developed from an ω-conotoxin isolated from cone snails. As marine biotechnologists are turning towards the immense range of novel bioproducts from
Cátia Gonçalves, Pedro M. Costa
doaj +1 more source
Staphylococcus aureus is an opportunistic bacterium of the human body and a leading cause of nosocomial infections. Methicillin resistant S. aureus (MRSA) infections involving biofilm lead to higher mortality and morbidity in patients.
Bhavana Gangwar +3 more
doaj +1 more source
A review prospective study: Exploring bounty marine biota bioprospecting [PDF]
The exploration of secondary metabolite compounds from marine biota has become an important research subject, as these resources are diverse. The purpose of this article is to provide an overview of bioprospection research on secondary metabolites in ...
Zamani Neviaty Putri +4 more
doaj +1 more source
We recognize the chemical composition of the acetonic extract of Rhizophora mangle barks (AERM) using mass spectrometry analysis [liquid chromatography (LC)–ESI–IT-MS/MS and matrix-assisted laser desorption/ionization-time of flight-MS (MALDI-TOF ...
Leonardo Mendes de Souza Mesquita +9 more
doaj +1 more source

