Cell-in-Bead-in-Droplet Platform for pH-Based Microfluidic Screening of Ureolytic Bacteria. [PDF]
Efficient high‐throughput microbial screening in droplet microfluidics is often challenged by chemical crosstalk between droplets. This is particularly difficult in pH‐changing biological processes, for which more effective biochemical assays are needed.
Giovanoli D +8 more
europepmc +2 more sources
Polyphasic Characterization of Acetobacter indonesiensis UNPADCC 01-5 Isolated From a Traditional Fermented Food, Oncom Merah. [PDF]
The polyphasic approach (morphology, physiology, biochemistry and genetics) was used to characterize Acetobacter indonesiensis strain UNPADCC 01‐5, which was isolated from oncom merah. The strain's potential as a culture for acidic fermentations and a biofunctional agent was supported by its adaptive characteristics, which included acid tolerance ...
Syaputri Y +9 more
europepmc +2 more sources
Bioprospecting Microbial Consortia for Tebuthiuron Degradation in Agricultural Soils: An Alternative Bayesian-Driven Colorimetric Protocol. [PDF]
Microbial consortia from sugarcane soils, particularly ratoon cane environments, showed tebuthiuron‐degrading potential. Bayesian factor estimation of kernel density curves based on logarithmic response ratios enabled interpretation of non‐sigmoidal spectrophotometric data, revealing native microbiota's bioremediation capacity and offering a novel ...
Jorososki LB +4 more
europepmc +2 more sources
Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants. [PDF]
The study workflow utilized validated in silico [molecular docking, fingerprinting, pharmacokinetics prediction, molecular dynamics (MD) simulation, ligand‐protein contact maps] tools to bioprospect a wide variety of metabolites surveyed from South African plants with antimicrobial activities, and target them against the key S.
Aruwa CE, Sabiu S.
europepmc +2 more sources
Ecology and bioprospecting [PDF]
AbstractBioprospecting is the exploration of biodiversity for new resources of social and commercial value. It is carried out by a wide range of established industries such as pharmaceuticals, manufacturing and agriculture as well as a wide range of comparatively new ones such as aquaculture, bioremediation, biomining, biomimetic engineering and ...
Beattie, Andrew J. +5 more
openaire +5 more sources
<i>In Silico</i> Bioprospection of <i>Daniellia oliveri-</i>Based Products as Quorum Sensing Modulators of <i>Escherichia coli</i> SdiA. [PDF]
Escherichia coli is a common pathogen responsible for various gut‐related infections, and it utilizes the SdiA‐mediated quorum sensing (QS) system to regulate biofilm formation, other virulence factors, and pathogenicity. With rising antibiotic resistance, there is a pressing need to discover alternative QS inhibitors (QSIs) targeting SdiA.
Dweba Y, Eleojo Aruwa C, Sabiu S.
europepmc +2 more sources
Discovering PETases: An Interlink Between Engineering Enzymes and Microbiomes. [PDF]
In this review‐type article, we discuss some recent trends in the identification of polyethylene terephthalate‐degrading enzymes (PETases) from nature. We highlight that the discovery of novel PETases can be improved by an interlink between reshaping microbiomes and engineering proteins.
Jiménez DJ, Rosado AS.
europepmc +2 more sources
Systematic bioprospection for cellulolytic actinomycetes in the Chihuahuan Desert: isolation and enzymatic profiling. [PDF]
The quest for microbial cellulases has intensified as a response to global challenges in biofuel production. The efficient deconstruction of lignocellulosic biomass holds promise for generating valuable products in various industries such as food ...
Escudero-Agudelo J +5 more
europepmc +2 more sources
Cephalotoxins: A Hotspot for Marine Bioprospecting?
Molluscs provided one of the pioneering approved pharmaceuticals from the seas: the painkiller ziconotide, developed from an ω-conotoxin isolated from cone snails. As marine biotechnologists are turning towards the immense range of novel bioproducts from
Cátia Gonçalves, Pedro M. Costa
doaj +1 more source

