Results 191 to 200 of about 28,179 (262)

Deciphering the Transcriptomic Signatures of Aging Across Organs in Mice

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Comprehensive transcriptomic profiling of eight mouse organs across six ages reveals how aging reshapes biological processes. Trajectory and network analyses distinguish shared and organ‐specific signatures, charting the molecular landscape of systemic aging.
Sarah Morsy   +9 more
wiley   +1 more source

Rapid Automated Immunohistochemistry on Frozen Sections Enables Real‐Time Surgical Pathology Decisions

open access: yesAPMIS, Volume 134, Issue 2, February 2026.
ABSTRACT Intraoperative frozen section (FS) analysis is critical in surgical pathology, but conventional hematoxylin and eosin (H&E) staining has limitations in poorly differentiated neoplasms and resection margins. Immunohistochemistry (IHC) provides higher diagnostic specificity, yet has traditionally been too time‐consuming for intraoperative ...
Camilla Christine Qvist   +6 more
wiley   +1 more source

Evolution of retiform hemangioendothelioma into angiosarcoma. [PDF]

open access: yesJAAD Case Rep
Hardy NJ   +4 more
europepmc   +1 more source

To VAE or not to VAE: outcomes of radial scars/complex sclerosing lesions and papillary lesions without atypia in the King's College Hospital breast service (2017–2023)

open access: yesHistopathology, Volume 88, Issue 3, Page 583-590, February 2026.
Radial scars/complex sclerosing lesions (RS/CSL) without atypia have a low upgrade rate (1%) and could possibly be monitored radiologically, thus avoiding excision. Papillary lesions without atypia have a higher upgrade rate (4%) and should continue to undergo vacuum excision until we better understand these heterogeneous lesions.
Amy Llewellyn   +3 more
wiley   +1 more source

GPNMB immunohistochemistry is a useful ancillary tool for the diagnosis of pulmonary lymphangioleiomyomatosis

open access: yesHistopathology, Volume 88, Issue 3, Page 698-709, February 2026.
We evaluated the diagnostic utility of GPNMB immunohistochemistry in LAM. GPNMB showed strong expression in LAM cells, while the differential diagnostic mimics showed no or only low expression. Based on its 100% sensitivity and specificity in our cohort, GPNMB is a highly reliable immunohistochemical marker for the diagnosis of LAM.
Fatime Szalai   +6 more
wiley   +1 more source

Breast Hemangioma with Slow Growth over 11 Years: A Case Report. [PDF]

open access: yesReports (MDPI)
Tabei A   +6 more
europepmc   +1 more source

Faecal microbiome, gastrointestinal integrity, inflammation and thermoregulation in recent exertional heat illness patients and matched controls

open access: yesExperimental Physiology, Volume 111, Issue 2, Page 403-425, 1 February 2026.
Abstract The gastrointestinal (GI) microbiota and GI barrier integrity are hypothesised to contribute to exertional heat illness (EHI) aetiology. We compared the faecal microbiome, GI barrier integrity, inflammation and thermoregulation of 29 recent (∼4 months) EHI patients (a group with elevated EHI risk) and 29 control individuals without prior EHI ...
Alex A. M. Gould   +13 more
wiley   +1 more source

Ex Vivo Evaluation of Sample Yields among New Semi-automatic, Conventional Semi-automatic, and Full-core Biopsy Needles. [PDF]

open access: yesInterv Radiol (Higashimatsuyama)
Endo Y   +7 more
europepmc   +1 more source

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