Results 111 to 120 of about 1,130,205 (306)

Microgel Aspect Ratio Influences Injectable Granular Hydrogel Scaffold Pore Structure and Cellular Invasion for Tissue Repair

Advanced Science, EarlyView.
Granular hydrogels are being developed for the repair of tissues, mostly with the use of spherical microgels. Here, injectable granular hydrogels formed from anisotropic particles (i.e., rod‐like) are explored to improve cellular invasion by increasing scaffold void volume fraction.
Gabriel J. Rodriguez‐Rivera, Siddharth Sharma, Chima V. Maduka, Sara Boyd, Amy R. Perry, Nikolas Di Caprio, Lindsay Riley, Connor E. Miksch, Daeyeon Lee, Tatiana Segura, David Issadore, Jason A. Burdick   +11 more
wiley   +1 more source

Decreased RYR2 Cluster Size and Abnormal SR Ca2+ Release Contribute to Arrhythmogenesis in TMEM43‐Related ARVC

Advanced Science, EarlyView.
The TMEM43 ‐ P386S mutation causes arrhythmogenic right ventricular cardiomyopathy (ARVC) by mislocalizing itself from nuclear envelope (NE) to cytoplasm, disrupting lamin B2 (a novel TMEM43 interactor) localization, NE integrity and chromatin accessibility, causing hyper ‐ phosphorylation and reduced expression/clustering of ryanodine receptor type 2 (
Jiaxi Shen, Xiaochen Wang, Hangping Fan, Yaxun Sun, Tingyu Gong, Hangyuan Qiu, Jue Wang, Ziwei Pan, Yanna Dang, Hongkun Wang, Danni Zhou, Tianyi Zhu, Hao Wang, Xianzhen Chen, Lizhen Xu, Jun Su, Fan Yang, Yiquan Tang, Xuguang Li, Bing Yang, Lenan Zhuang, Wei Wang, Chenyang Jiang, Ping Liang   +23 more
wiley   +1 more source

Precision Tumor Recognition in Clear Cell Renal Cell Carcinoma: A qHCR Platform Leveraging Tetrahedral DNA Nanostructures for Rapid Molecular Diagnosis

Aggregate, EarlyView.
A tetrahedral DNA nanostructure‐based quadrivalent hybridization chain reaction (qHCR) platform is developed for rapid and precise diagnosis of renal tumors during surgery, postoperatively, and in biopsy samples. Intraoperative detection ensures an optimal balance between molecular diagnosis and ischemia time control, providing efficient support for ...
Chenyu Wang, Yongji Li, Haorui Li, Jing Wang, Weida Liu, Jiarui Su, Ronghao Cui, Siwei Yang, Zhili Yao, Qingnan Li, Guimei Han, Jianxi Shi, Zheng Zhang, Zhun Wang, Zhifei Liu, Yegang Chen, Shuangqing Liu, Yan Zhao, Shaosan Kang, Deming Kong, Qiliang Cai   +20 more
wiley   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

CT-Guided Transthoracic Biopsy of Lung Lesions Using a Non-Coaxial Biopsy Needle Technique: CT Characteristics Predictive for Diagnostic Accuracy and Pneumothorax. [PDF]

J Belg Soc Radiol, 2021
Geeroms B, Cockmartin L, Coolen J, Dubbeldam A, Verschakelen J, Nikoghosyan A, De Wever W.   +6 more
europepmc   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Prospective study of EUS-guided tissue acquisition with a 20G core biopsy needle with a forward bevel for solid pancreatic mass. [PDF]

Medicine (Baltimore), 2021
Kanata R, Sasaki T, Matsuyama M, Ishigaki K, Yamada I, Ozaka M, Takano K, Takazawa Y, Ishizuka N, Sasahira N.   +9 more
europepmc   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu, Zhiwei Fang, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren, Wu Yuan   +7 more
wiley   +1 more source

Effectiveness of introducing a 20-gauge core biopsy needle with a core trap in EUS-FNA/B for diagnosing pancreatic cancer. [PDF]

BMC Gastroenterol, 2021
Watanabe S, Miyoshi J, Toki M, Kambayashi K, Kitada S, Nosaka T, Goto T, Ota H, Ochiai K, Gondo K, Ikeuchi N, Tsuji S, Nakamura K, Shibahara J, Hisamatsu T.   +14 more
europepmc   +1 more source

Robotic Interventional Needle Insertion Assisted by a Cable‐Driven Parallel Robot

Advanced Intelligent Systems, EarlyView.
This article presents a body‐mounted cable‐driven parallel robot assisting the needle insertion procedure designated for automated interventional pain therapy. The 3D‐printed robot body and multiple thin cables can achieve high X‐ray compatibility for intervention. The robot performs full 6‐degree of freedom needle insertion and remote center of motion
Myungjin Jung, Sejeong Kim, Min‐Cheol Kim, Hyun‐Jung Kwon, Jaesoon Choi, Chang‐Sei Kim   +5 more
wiley   +1 more source