Results 91 to 100 of about 1,503,790 (360)

Evaluation of an epigenetic assay for predicting repeat prostate biopsy outcome in African American men [PDF]

, 2019
OBJECTIVE: To evaluate an epigenetic assay performed on tissue from negative prostate biopsies in a group of African American (AA) men undergoing repeat biopsy, and to compare accuracy for predicting repeat biopsy outcome to prior studies conducted in ...
Anglade, Ronald, Barnswell, Carlton, Carter, Michael, Groskopf, Jack, Jalkut, Mark, Krispin, Manuel, Moses, Kelvin A, Murdock, Myron, Shah, Nikhil, Shiffman, Zvi, Silberstein, Jonathan L, Sylora, James, Tutrone, Ronald, Van Criekinge, Wim, Van Neste, Leander, Vandenberg, Todd, Waterhouse, Robert L, Jr   +16 more
core   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Cancer in a drop: Liquid biopsy highlights from the American Society of Clinical Oncology (ASCO) 2025 annual congress

The Journal of Liquid Biopsy
Over the past decade, liquid biopsy has progressively expanded its role in oncology, supported by mounting evidence demonstrating an increasing number of clinical applications.
Canio Martinelli, Roberto Borea, Maheswaran Shivahamy, Angelo Dipasquale, Erick F. Saldanha, Nadia Ghazali, Eleonora Nicolo, Pavel Stejskal, Letizia Pontolillo, Carolina Reduzzi   +9 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A comprehensive evaluation of colonic mucosal isolates of Sutterella wadsworthensis from inflammatory bowel disease [PDF]

, 2011
Peer reviewedPublisher ...
AF Haag, B Khor, Charlotte E. Nicholl, Craig Pattinson, David A. Stead, E Molitoris, Emad M. El-Omar, EN Ilina, Georgina L. Hold, GL Hold, H Sakon, H Sokol, HL Greetham, HM Wexler, I Mangin, I Mukhopadhya, Indrani Mukhopadhya, J Engberg, JG Fox, JM Thomson, John M. Thomson, L Zhang, LB Reller, LD Kalischuk, M Alispahic, MB Skirrow, MF Andreasen, MS Silverberg, MV Selma, P Lasch, P Marteau, R Hansen, R Hansen, R Kolinska, Richard Hansen, Richard K. Russell, S Kumar, S Rozen, S Schippa, Stefan Bereswill, Susan H. Berry, Yazeid A. Alhaidan   +41 more
core   +4 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Heterogeneity of monosomy 3 in fine needle aspiration biopsy of choroidal melanoma. [PDF]

, 2013
PurposeTo report on the heterogeneity of monosomy 3 in a fine needle aspiration biopsy obtained transsclerally from choroidal melanoma for prognosis.MethodsAll clinical records for patients who had been diagnosed with choroidal melanoma and underwent ...
Burgess, Barry L, Chang, Melinda Y, Johnson, Lariza, McCannel, Tara A, Rao, Nagesh P   +4 more
core   +2 more sources

An Open-Source 7-Axis, Robotic Platform to Enable Dexterous Procedures within CT Scanners

, 2019
This paper describes the design, manufacture, and performance of a highly dexterous, low-profile, 7 Degree-of-Freedom (DOF) robotic arm for CT-guided percutaneous needle biopsy.
Norbash, Alexander M., Schreiber, Dimitri A., Shak, Daniel B., Yip, Michael C.   +3 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Cereal and nonfat milk support muscle recovery following exercise [PDF]

, 2009
All authors are with the Exercise Physiology and Metabolism Laboratory Department of Kinesiology and Health Education The University of Texas at Austin Austin, TX, USABackground: This study compared the effects of ingesting cereal and nonfat milk (Cereal)
Ding, Zhenping, Hara, Daiske, Ivy, John L., Kammer, Lynne, Liao, Yi-Hung, Wang, Bei   +5 more
core   +3 more sources