Results 281 to 290 of about 1,636,979 (366)

Protocol Biopsies in Delayed Graft Function Kidney Transplants From Brain-Dead Donors. [PDF]

Clin Transplant
Ahlmark A, Sallinen V, Räisänen-Sokolowski A, Ahopelto K, Lempinen M, Lauronen J, Helanterä I.   +6 more
europepmc   +1 more source

Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction

Advanced Science, EarlyView.
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod, Ryan N. Stack, Sarah E. Kubik, Stephanie A. Huang, Chloe P. Whitworth, Wen Y. Aw, Elizabeth L. Doherty, Sara M. Meehan, Prabir Roy‐Chaudhury, William J. Polacheck   +9 more
wiley   +1 more source

Cancer in a Drop: Liquid biopsy insights from AACR 2025

The Journal of Liquid Biopsy
Shivahamy Maheswaran, Roberto Borea, Diego de Miguel Perez, Pasquale Pisapia, Nadia Ghazali, Canio Martinelli, Pavel Stejskal, Carolina Reduzzi   +7 more
doaj  

A Deep Learning Model Integrating Clinical and MRI Features Improves Risk Stratification and Reduces Unnecessary Biopsies in Men with Suspected Prostate Cancer. [PDF]

Cancers (Basel)
Bacchetti E, De Nardin A, Giannarini G, Cereser L, Zuiani C, Crestani A, Girometti R, Foresti GL.   +7 more
europepmc   +1 more source

Rictor Ameliorates Acute Antibody‐Mediated Rejection Following Kidney Transplantation by Suppressing Macrophage M1 Polarization Through p65‐NLRP3 Axis

Advanced Science, EarlyView.
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni, Chengcheng Yang, Junqi Zhang, Zhou Hang, Ming Zheng, Dengyuan Feng, Qinghuan Shen, Jinxu Miao, Xulin Sun, Li Sun, Baixin Shen, Min Gu, Zijie Wang   +12 more
wiley   +1 more source

Fibrillary glomerulonephritis disease natural history and outcomes: a retrospective two centre cohort study. [PDF]

BMC Nephrol
Zhang Y, Baharani J, Ajayi B, Pinney J.
europepmc   +1 more source

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source

Lymphadenectomy and Sentinel Lymph Node Biopsy in Patients with Endometrial Cancer in Intermediate and High-Intermediate Risk Groups: The Ukrainian Experience. [PDF]

Int J Womens Health
Khoptiana O, Svintsitskyi V, Nespryadko S, Tsip NP, Gogisvanidze T, Dzimistarishvili M, Krasylenko D, Chetverikov MS, Nigutsa IP, Sumtsov D, Dolyk P.   +10 more
europepmc   +1 more source

ACSS2‐Mediated Histone H4 Lysine 12 Crotonylation (H4K12cr) Alleviates Colitis via Enhancing Transcription of CLDN7

Advanced Science, EarlyView.
Histone lysine crotonylation (Kcr) is a highly conserved posttranslational modification implicated with crucial biological processes. This study reveals that ACSS2‐mediated H4K12cr upregulated CLDN7 transcription to strengthen intestinal epithelial barrier.
Ming Yuan, Shaopeng Chen, Zhensen Lin, Runfeng Yu, Kang Chao, Shubiao Ye, Qing Li, Haoxian Ke, Chi Zhang, Junfeng Huang, Guanzhan Liang, Tuo Hu, Xiang Gao, Ping Lan, Xianrui Wu   +14 more
wiley   +1 more source