Results 21 to 30 of about 2,118,431 (433)

Circulating Tumor DNA as a Cancer Biomarker: An Overview of Biological Features and Factors That may Impact on ctDNA Analysis

Frontiers in Oncology, 2022
Cancer cells release nucleic acids, freely or associated with other structures such as vesicles into body fluids, including blood. Among these nucleic acids, circulating tumor DNA (ctDNA) has emerged as a minimally invasive biomarker for tumor molecular ...
Estela Sánchez-Herrero, Estela Sánchez-Herrero, Roberto Serna-Blasco, Lucia Robado de Lope, Víctor González-Rumayor, Atocha Romero, Atocha Romero, Mariano Provencio, Mariano Provencio   +8 more
doaj   +1 more source

Ivermectin induces apoptosis of esophageal squamous cell carcinoma via mitochondrial pathway

BMC Cancer, 2021
Background Esophageal squamous cell carcinoma (ESCC) is the most predominant primary malignant tumor among worldwide, especially in China. To date, the successful treatment remains a mainly clinical challenge, it is imperative to develop successful ...
Nana Xu, Mengmeng Lu, Jiaxin Wang, Yujia Li, Xiaotian Yang, Xiajie Wei, Jiaoyang Si, Jingru Han, Xiaojuan Yao, Juanmei Zhang, Junqi Liu, Yanming Li, Hushan Yang, Dengke Bao   +13 more
doaj   +1 more source

Mucinous Cystadenoma of the Ovary Associated with Hyperplasia of Stromal Leydig Cells in Pregnant Woman

Galician Medical Journal, 2021
Background: The hormonally induced non-neoplastic lesions of ovarian stroma during pregnancy must be recognized by pathologist in order to avoid mistaking them for true tumors.
Vladimír Bartoš
doaj   +1 more source

Immunohistochemical Expression of IMP3 in Cutaneous Basal Cell Carcinoma

Galician Medical Journal, 2022
Background. Insulin-like growth factor-II mRNA-binding protein 3 (IMP3) is an oncofetal protein upregulated in tumor cells during carcinogenesis. It has been linked to adverse clinical outcome in many malignancies.
Vladimir Bartos
doaj   +1 more source

MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis.

New England Journal of Medicine, 2020
BACKGROUND The use of 12-core systematic prostate biopsy is associated with diagnostic inaccuracy that contributes to both overdiagnosis and underdiagnosis of prostate cancer.
M. Ahdoot, Andrew R Wilbur, Sarah E Reese, A. Lebastchi, Sherif Mehralivand, Patrick T. Gomella, Jonathan B Bloom, Sandeep Gurram, M. Siddiqui, P. Pinsky, H. Parnes, W. Linehan, M. Merino, P. Choyke, J. Shih, B. Turkbey, B. Wood, P. Pinto   +17 more
semanticscholar   +1 more source

Mortality in Biopsy-Confirmed Nonalcoholic Fatty Liver Disease

Gut, 2020
Objective Population-based data are lacking regarding the risk of overall and cause-specific mortality across the complete histological spectrum of non-alcoholic fatty liver disease (NAFLD).
Tracey G. Simon, B. Roelstraete, H. Khalili, H. Hagström, J. Ludvigsson   +4 more
semanticscholar   +1 more source

Application of exosomes as liquid biopsy in clinical diagnosis

Signal Transduction and Targeted Therapy, 2020
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small extracellular vesicles with sizes between 30–150 nm.
Biting Zhou, Kailun Xu, Xi Zheng, Ting Chen, Jian Wang, Yong-mao Song, Yingkuan Shao, Shu Zheng   +7 more
semanticscholar   +1 more source

Genomic landscape and survival analysis of ctDNA “neo-RAS wild-type” patients with originally RAS mutant metastatic colorectal cancer

Frontiers in Oncology, 2023
BackgroundThe term “neo-RAS wild-type” refers to the switch to RAS wild-type disease in plasma circulating tumor DNA (ctDNA) from originally RAS mutant colorectal cancers.
Chiara Nicolazzo, Valentina Magri, Luca Marino, Francesca Belardinilli, Federica Di Nicolantonio, Gianluigi De Renzi, Salvatore Caponnetto, Michela De Meo, Giuseppe Giannini, Daniele Santini, Enrico Cortesi, Paola Gazzaniga   +11 more
doaj   +1 more source

Kidney Biopsy Findings in Patients with COVID-19.

Journal of the American Society of Nephrology, 2020
BACKGROUND Coronavirus disease 2019 (COVID-19) is thought to cause kidney injury by a variety of mechanisms. To date, pathologic analyses have been limited to patient reports and autopsy series.
Satoru Kudose, Ibrahim Batal, D. Santoriello, Katherine Xu, J. Barasch, Yonatan Peleg, P. Canetta, Lloyd E. Ratner, M. Marasà, A. Gharavi, M. Stokes, G. Markowitz, Vivette D. D'Agati   +12 more
semanticscholar   +1 more source

MRI-Targeted or Standard Biopsy in Prostate Cancer Screening.

New England Journal of Medicine, 2021
BACKGROUND High rates of overdiagnosis are a critical barrier to organized prostate cancer screening. Magnetic resonance imaging (MRI) with targeted biopsy has shown the potential to address this challenge, but the implications of its use in the context ...
M. Eklund, F. Jäderling, A. Discacciati, M. Bergman, M. Annerstedt, M. Aly, A. Glaessgen, S. Carlsson, H. Grönberg, T. Nordström   +9 more
semanticscholar   +1 more source