Results 41 to 50 of about 1,142,488 (304)

Circular RNAs Are Promising Biomarkers in Liquid Biopsy for the Diagnosis of Non-small Cell Lung Cancer

Frontiers in Molecular Biosciences, 2021
The high incidence and mortality of lung cancer make early detection of lung cancer particularly important. At present, the diagnosis of lung cancer mainly depends on diagnostic imaging and tissue biopsy. However, current diagnostics are not satisfactory
Lanxiang Huang, Lanxiang Huang, Yuan Rong, Yuan Rong, Xuan Tang, Xuan Tang, Kezhen Yi, Kezhen Yi, Jianyuan Wu, Fubing Wang, Fubing Wang, Fubing Wang   +11 more
doaj   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Hemp Seed-Derived Vesicle-like Nanoparticles Modulate Dermal Collagen Homeostasis and Attenuate UVB-Induced Photoaging-Related Responses

Molecules
Plant-derived extracellular vesicle-like nanoparticles (EVNPs) have emerged as bioactive nanomaterials with potential applications in skin biology; however, their isolation from complex plant matrices and their integrated biological effects remain ...
Hannah S. Park, Sehyun Shin
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Clinical Efficacy and Safety Evaluation of a Centella asiatica (CICA)-Derived Extracellular Vesicle Formulation for Anti-Aging Skincare

Cosmetics
Centella asiatica (CICA)-derived exosomes have emerged as bioactive agents for skin rejuvenation due to their regenerative and anti-inflammatory properties.
Hannah S. Park, Sehyun Shin
doaj   +1 more source

Transjugular liver biopsy: how good is it for accurate histological interpretation? [PDF]

, 2006
Background: A transjugular liver biopsy (TJLB) specimen is often smaller or more fragmented than a percutaneous liver biopsy (PLB) specimen. Recently, for PLB, the minimum requirements to evaluate chronic hepatitis have been set at 20–25 mm length and 11
Leandro, G., Patch, D., Dhillon, A.P., Cholongitas, E., Quaglia, A., Triantos, C., Samonakis, D., Burroughs, A.K., Senzolo, M.   +8 more
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CT-guided transthoracic biopsy: histopathologic results and complication rates [PDF]

, 2015
PURPOSEWe aimed to investigate the effectiveness and complications of transthoracic CT-guided biopsy techniques.METHODSA total of 94 CT-guided percutaneous transthoracic biopsy procedures performed in 85 patients were retrospectively evaluated.
Bumin Değirmenci, Emel Gözlek, Hakan Demirtaş, Ömer Yılmaz, Nisa Ünlü, Aykut Recep Aktaş, Mustafa Kayan, Mustafa Kara   +7 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma

Cell Death and Disease, 2021
TEFM (transcription elongation factor of mitochondria) has been identified as a novel nuclear-encoded transcription elongation factor in the transcription of mitochondrial genome.
Lixin Wan, Yang Wang, Zijie Zhang, Jiaxin Wang, Menglan Niu, Yuanyuan Wu, Yating Yang, Yongxia Dang, Shuang Hui, Meng Ni, Bo Wan, Dengke Bao   +11 more
doaj   +1 more source

Liquid biopsy from research to clinical practice : focus on non-small cell lung cancer

, 2021
: Introduction In the current era of personalized medicine, liquid biopsy has acquired a relevant importance in patient management of advanced stage non-small cell lung cancer (NSCLC).
Pisapia, Pasquale, De Miguel-Perez, Diego, Nuzzo, Pier Vitale, Addeo, Alfredo, Jantus-Lewintre, Eloisa, Rolfo, Christian, Bellosillo, Beatriz, Serrano, Maria Jose, Malapelle, Umberto, Arrieta, Oscar, Cardona, Andres F., Denninghoff, Valeria, Pauwels, Patrick, Troncone, Giancarlo, Raez, Luis E., Gandara, David R., Duran, Ignacio, Pickering, Edward M., Russo, Alessandro, Cristofanilli, Massimo, O'Byrne, Ken   +20 more
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