Results 41 to 50 of about 1,110,149 (259)

Dynamic gene screening enabled identification of a 10-gene panel for early detection and progression assessment of gastric cancer

Computational and Structural Biotechnology Journal, 2023
Early diagnosis and progression assessment are critical for the timely detection and treatment of gastric cancer (GC) patients. Identification of diagnostic biomarkers for early detection of GC represents an unmet clinical need, and how these markers ...
Fei Long, Shuo Li, Yaqi Xu, Min Liu, Xuan Zhang, Junting Zhou, Yiyi Chen, Yuan Rong, Xiangyu Meng, Fubing Wang   +9 more
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

The potential of hydrogel‐free tumoroids in head and neck squamous cell carcinoma

Cancer Medicine
Background Head and neck malignancy, and in particular squamous cell carcinoma (SCC), is responsible for a significant disease burden globally. The lack of an optimal in vitro model system to accurately recapitulate in vivo response to therapy in HNSCC ...
Michael Wong, Sarju Vasani, Omar Breik, Xi Zhang, Lizbeth Kenny, Chamindie Punyadeera   +5 more
doaj   +1 more source

Artificial intelligence-generated hip radiological measurements are fast and adequate for reliable assessment of hip dysplasia an external validation study

Bone & Joint Open, 2022
AimsHip dysplasia (HD) leads to premature osteoarthritis. Timely detection and correction of HD has been shown to improve pain, functional status, and hip longevity. Several time-consuming radiological measurements are currently used to confirm HD.
Holden Archer, Seth Reine, Ahmed Alshaikhsalama, Joel Wells, Ajay Kohli, Louis Vazquez, Allan Hummer, Matthew D. DiFranco, Richard Ljuhar, Yin Xi, Avneesh Chhabra   +10 more
doaj   +1 more source

Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega, Daniel J. Indelicato, Jeanette Parkes, Natia Esiashvili, Josué Hernández Benítez, Miriam Mikhail‐Lette, Olivera Cirajc Bjelac, Daniel Berger, Eva Ciurana, Yavuz Anacak, Lisbeth Cordero‐Mendez   +10 more
wiley   +1 more source

Liquid biopsy from research to clinical practice : focus on non-small cell lung cancer

, 2021
: Introduction In the current era of personalized medicine, liquid biopsy has acquired a relevant importance in patient management of advanced stage non-small cell lung cancer (NSCLC).
Pisapia, Pasquale, De Miguel-Perez, Diego, Nuzzo, Pier Vitale, Addeo, Alfredo, Jantus-Lewintre, Eloisa, Rolfo, Christian, Bellosillo, Beatriz, Serrano, Maria Jose, Malapelle, Umberto, Arrieta, Oscar, Cardona, Andres F., Denninghoff, Valeria, Pauwels, Patrick, Troncone, Giancarlo, Raez, Luis E., Gandara, David R., Duran, Ignacio, Pickering, Edward M., Russo, Alessandro, Cristofanilli, Massimo, O'Byrne, Ken   +20 more
core  

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

TEFM facilitates uterine corpus endometrial carcinoma progression by activating ROS-NFκB pathway

Journal of Translational Medicine
Background Mitochondrial transcription elongation factor (TEFM) is a recently discovered factor involved in mitochondrial DNA replication and transcription.
Jia Lei, Qingguo Zhu, Jianghao Guo, Jiaxing Chen, Lixia Qi, Mengmeng Cui, Zhixiong Jiang, Chunhui Fan, Lin Wang, Tianjiao Lai, Yuxi Jin, Lulu Si, Yana Liu, Qi Yang, Dengke Bao, Ruixia Guo   +15 more
doaj   +1 more source

Transcriptional profiles of circulating tumor cells reflect heterogeneity and treatment resistance in advanced prostate cancer

Journal of Experimental & Clinical Cancer Research
Purpose New biomarkers for the detection and monitoring of aggressive variant prostate cancer (AVPC) including therapy-induced neuroendocrine prostate cancer (NEPC) are urgently needed, as measuring prostate-specific antigen (PSA) is not reliable in ...
Lina Bergmann, Sarah Greimeier, Sabine Riethdorf, Tina Rohlfing, Moritz Kaune, Tobias Busenbender, Nadja Strewinsky, Sergey Dyshlovoy, Simon Joosse, Sven Peine, Klaus Pantel, Gunhild von Amsberg, Stefan Werner   +12 more
doaj   +1 more source

Inferior vena cava/aorta diameter index in the assessment of the body fluid status – a comparative study of measurements performed by experienced and inexperienced examiners in a group of young adults

Journal of Ultrasonography, 2014
The assessment of the body fluid status is one the most challenging tasks in clinical practice. Although there are many methods to assess the body fluid status of patients, none of them is fully satisfactory in contemporary medical sciences.
Kaja Durajska, Emilia Januszkiewicz, Łukasz Szmygel, Wojciech Kosiak   +3 more
doaj   +1 more source