Results 61 to 70 of about 1,110,149 (259)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. [PDF]

, 2013
OBJECTIVES: To study muscle biopsy tissue from patients with juvenile dermatomyositis (JDM) in order to test the reliability of a score tool designed to quantify the severity of histological abnormalities when applied to biceps humeri in addition to ...
Pilkington, Clarissa A, Varsani, Hemlata, Marie, Suely KN, Lundberg, Ingrid E, Sallum, Adriana M E, Banwell, Brenda, Sallum, Adriana ME, Corse, Andrea M, Charman, Susan C, Jacques, Thomas S, Amato, Anthony A, Bove, Kevin E, Emslie-Smith, Alison M, Marie, Suely K N, Holton, Janice L, Nennesmo, Inger, Rushing, Elisabeth J, UK Juvenile Dermatomyositis Research Group, Li, Charles K, Amato, Anthony, Minetti, Carlo, Sewry, Caroline, Wedderburn, Lucy R, Bove, KE, Banwell, B, Varsani, H, Emslie-Smith, AM, Marie, SKN, Corse, AM, Li, CK, Jacques, TS, Amato, AA, Charman, SC   +32 more
core   +1 more source

Sonographic assessment of the inferior vena cava/aorta index measured with the transducer placed in the anterior median line and right anterior axillary line – a comparison

Journal of Ultrasonography, 2014
The aim of the study was to compare the values of the sonographic inferior vena cava/ aorta index obtained with the transducer placed in the median line and right anterior axillary line. Material and methods: The study enrolled 45 volunteers, including
Monika Luboch, Magdalena Łoś, Łukasz Szmygel, Wojciech Kosiak   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Use of a hemostasis introducer sheath to guide clip delivery during stereotactic directional vacuum-assisted breast biopsy when the biopsy system malfunctions

, 2011
Stereotactic directional vacuum-assisted breast biopsy (ST DVAB) is an accurate biopsy method. Marking the biopsy site with a clip is mandatory after ST DVAB, in case excision is required.
王甄;張君如, WANG, JANE;CHANG, CHUN-JU   +1 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Dual-camera infrared guidance for computed tomography biopsy procedures [PDF]

, 2017
A CT-guided biopsy is a specialised surgical procedure whereby a needle is used to withdraw tissue or fluid specimen from a lesion of interest. The needle is guided while being viewed by a clinician on a computed tomography (CT) scan.
Shar, Bruce
core   +1 more source

DNA Methylation Changes in Human Papillomavirus-Driven Head and Neck Cancers

Cells, 2020
Disruption of DNA methylation patterns is one of the hallmarks of cancer. Similar to other cancer types, human papillomavirus (HPV)-driven head and neck cancer (HNC) also reveals alterations in its methylation profile.
Chameera Ekanayake Weeramange, Kai Dun Tang, Sarju Vasani, Julian Langton-Lockton, Liz Kenny, Chamindie Punyadeera   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Biopsy in Ocular Oncology

, 2014
Biopsy of a mass lesion implies tissue sampling for histopathologic examination. Tissue sampling can be done with different methodologies. Biopsy techniques include excisional, incisional, core, aspiration biopsies as well as intraoperative biopsy with ...
Fatma Akbaş Kocaoğlu
core   +1 more source