Results 51 to 60 of about 1,027,892 (313)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

TEFM facilitates uterine corpus endometrial carcinoma progression by activating ROS-NFκB pathway

Journal of Translational Medicine
Background Mitochondrial transcription elongation factor (TEFM) is a recently discovered factor involved in mitochondrial DNA replication and transcription.
Jia Lei, Qingguo Zhu, Jianghao Guo, Jiaxing Chen, Lixia Qi, Mengmeng Cui, Zhixiong Jiang, Chunhui Fan, Lin Wang, Tianjiao Lai, Yuxi Jin, Lulu Si, Yana Liu, Qi Yang, Dengke Bao, Ruixia Guo   +15 more
doaj   +1 more source

Current Status and Future Perspectives of Liquid Biopsy in Small Cell Lung Cancer

Biomedicines, 2021
Approximately 19% of all cancer-related deaths are due to lung cancer, which is the leading cause of mortality worldwide. Small cell lung cancer (SCLC) affects approximately 15% of patients diagnosed with lung cancer.
Patricia Mondelo-Macía, Jorge García-González, Luis León-Mateos, Adrián Castillo-García, Rafael López-López, Laura Muinelo-Romay, Roberto Díaz-Peña   +6 more
doaj   +1 more source

Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. [PDF]

, 2013
OBJECTIVES: To study muscle biopsy tissue from patients with juvenile dermatomyositis (JDM) in order to test the reliability of a score tool designed to quantify the severity of histological abnormalities when applied to biceps humeri in addition to ...
Pilkington, Clarissa A, Varsani, Hemlata, Marie, Suely KN, Lundberg, Ingrid E, Sallum, Adriana M E, Banwell, Brenda, Sallum, Adriana ME, Corse, Andrea M, Charman, Susan C, Jacques, Thomas S, Amato, Anthony A, Bove, Kevin E, Emslie-Smith, Alison M, Marie, Suely K N, Holton, Janice L, Nennesmo, Inger, Rushing, Elisabeth J, UK Juvenile Dermatomyositis Research Group, Li, Charles K, Amato, Anthony, Minetti, Carlo, Sewry, Caroline, Wedderburn, Lucy R   +22 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Transcriptional profiles of circulating tumor cells reflect heterogeneity and treatment resistance in advanced prostate cancer

Journal of Experimental & Clinical Cancer Research
Purpose New biomarkers for the detection and monitoring of aggressive variant prostate cancer (AVPC) including therapy-induced neuroendocrine prostate cancer (NEPC) are urgently needed, as measuring prostate-specific antigen (PSA) is not reliable in ...
Lina Bergmann, Sarah Greimeier, Sabine Riethdorf, Tina Rohlfing, Moritz Kaune, Tobias Busenbender, Nadja Strewinsky, Sergey Dyshlovoy, Simon Joosse, Sven Peine, Klaus Pantel, Gunhild von Amsberg, Stefan Werner   +12 more
doaj   +1 more source

Inferior vena cava/aorta diameter index in the assessment of the body fluid status – a comparative study of measurements performed by experienced and inexperienced examiners in a group of young adults

Journal of Ultrasonography, 2014
The assessment of the body fluid status is one the most challenging tasks in clinical practice. Although there are many methods to assess the body fluid status of patients, none of them is fully satisfactory in contemporary medical sciences.
Kaja Durajska, Emilia Januszkiewicz, Łukasz Szmygel, Wojciech Kosiak   +3 more
doaj   +1 more source

Cost-effectiveness analysis of capecitabine maintenance therapy plus best supportive care vs. best supportive care alone as first-line treatment of newly diagnosed metastatic nasopharyngeal carcinoma

Frontiers in Public Health, 2023
ObjectivesMaintenance therapy with capecitabine after induction chemotherapy for patients with newly diagnosed metastatic nasopharyngeal carcinoma (mNPC) has been confirmed to be effective.
Jiaqi Han, Xiaomeng Lan, Kun Tian, Xi Shen, Jinlan He, Nianyong Chen   +5 more
doaj   +1 more source

Fibroadenoma: to biopsy or not to biopsy? That is the question [PDF]

Breast Cancer Research, 2012
In 2011, our institution adopted the policy (in line with national guidance) not to biopsy breast masses in patients
Karuppiah, AS, Bugg, WG, Juette, A
openaire   +1 more source

Use of a hemostasis introducer sheath to guide clip delivery during stereotactic directional vacuum-assisted breast biopsy when the biopsy system malfunctions

, 2011
Stereotactic directional vacuum-assisted breast biopsy (ST DVAB) is an accurate biopsy method. Marking the biopsy site with a clip is mandatory after ST DVAB, in case excision is required.
王甄;張君如, WANG, JANE;CHANG, CHUN-JU   +1 more
core   +1 more source