Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex +13 more
wiley +1 more source
Precision prevention and cancer interception : the new challenges of liquid biopsy [PDF]
: Despite major therapeutic progress, most advanced solid tumors are still incurable. Cancer interception is the active way to combat cancer onset, and development of this approach within high-risk populations seems a logical first step.
Lorente, Jose A. +14 more
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ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen +21 more
wiley +1 more source
The potential of hydrogel‐free tumoroids in head and neck squamous cell carcinoma
Background Head and neck malignancy, and in particular squamous cell carcinoma (SCC), is responsible for a significant disease burden globally. The lack of an optimal in vitro model system to accurately recapitulate in vivo response to therapy in HNSCC ...
Michael Wong +5 more
doaj +1 more source
Prostate biopsy for diagnosis of prostate carcinoma [PDF]
MRI/US guided biopsy,TRUS biopsyáltalános orvosangolegységes ...
Derakhshandehbakht, Ali
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Biopsy-based calibration of T2* magnetic resonance for estimation of liver iron concentration and comparison with R2 Ferriscan [PDF]
There is a need to standardise non-invasive measurements of liver iron concentrations (LIC) so clear inferences can be drawn about body iron levels that are associated with hepatic and extra-hepatic complications of iron overload.
Alam, MH +15 more
core +1 more source
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
TEFM facilitates uterine corpus endometrial carcinoma progression by activating ROS-NFκB pathway
Background Mitochondrial transcription elongation factor (TEFM) is a recently discovered factor involved in mitochondrial DNA replication and transcription.
Jia Lei +15 more
doaj +1 more source
Current Status and Future Perspectives of Liquid Biopsy in Small Cell Lung Cancer
Approximately 19% of all cancer-related deaths are due to lung cancer, which is the leading cause of mortality worldwide. Small cell lung cancer (SCLC) affects approximately 15% of patients diagnosed with lung cancer.
Patricia Mondelo-Macía +6 more
doaj +1 more source
Biopsy interpretation of the thyroid Biopsy interpretation series./ Scott Boerner, Sylvia L. Asa. [PDF]
The normal thyroid -- The classification of thyroid pathology -- The cytologic approach to diagnosis of thyroid pathology : technical aspects -- The histologic biopsy of thyroid : technical aspects -- Ancillary tools in thyroid diagnosis -- Cystic ...
Boerner Scott L.,, Asa Sylvia L.,
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