Results 111 to 120 of about 230,956 (200)
Obesity Reviews, EarlyView.ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares +4 more
wiley +1 more source
Disruption of Asparagine Synthetase Is Associated to Increased Biomass in Lotus japonicus
Plant Biotechnology Journal, EarlyView.ABSTRACT Asparagine (Asn) constitutes the major form of nitrogen translocated within Lotus japonicus plants. In this work we use knock‐out (KO) LORE1 mutants‐deficient in the asparagine synthetase gene (LjASN1), which is the most highly expressed ASN gene in plants grown under non‐symbiotic (NS) conditions, but much less expressed under symbiotic (S ...
Sara Rosa‐Téllez +5 more
wiley +1 more source
Human Frataxin Folds Via an Intermediate State. Role of the C-Terminal Region [PDF]
, 2016 The aim of this study is to investigate the folding reaction of human frataxin, whose deficiency causes the neurodegenerative disease Friedreich’s Ataxia (FRDA).
Faraj, Santiago Enrique +3 more
core +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Lysine represents a metabolic hub linking mitochondrial energy status with amino acid catabolism, yet its role in coordinating plant growth and development remains poorly characterised. The dapat mutant, which is deficient in L,L‐diaminopimelate aminotransferase (DAPAT), exhibits severe growth inhibition associated with broad metabolic ...
Débora Gonçalves Gouveia +10 more
wiley +1 more source
Dr. Rolando Hernández Fernández: paradigma en la Educación Médica Superior Cubana
Revista Habanera de Ciencias Médicas, 2022 En la trayectoria profesional del Dr. Rolando Aníbal Hernández Fernández destacan notablemente la elaboración e implementación de planes de estudio en las carreras de Ciencias de la Salud y en las especialidades de Bioquímica Clínica y Genética Médica ...
Hector Julio Piñera-Castro +1 more
doaj
Sphingomyelin metabolism is involved in the differentiation of MDCK cells induced by environmental hypertonicity [PDF]
, 2015 Sphingolipids (SLs) are relevant lipid components of eukaryotic cells. Besides regulating various cellular processes, SLs provide the structural framework for plasma membrane organization.
Favale, Nicolas Octavio +4 more
core +1 more source
Photochemistry and Photobiology, EarlyView.Gadusol‐rich extracts provide effective UVB protection and antioxidant activity in HaCaT cells and C. elegans, highlighting their potential as natural photochemoprotective agents for pharmaceutical and cosmetic applications. It also demonstrates remarkable in vitro antioxidant capacity and thermal stability over time.
Rocío Isla Naveira +9 more
wiley +1 more source
Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes
Photochemistry and Photobiology, EarlyView.Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto +8 more
wiley +1 more source
Plant Biology, EarlyView.Natural Arabidopsis thaliana accessions showed remarkable plasticity in both life‐cycle phenology and whole‐genome gene expression patterns in in natura field experiments. Nevertheless, local adaptation in fitness‐related life‐history traits can also be detected at the whole‐genome gene expression level.
A. Martínez‐Pérez +8 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 1, Page 144-158, 1 July 2026.What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho +7 more
wiley +1 more source