Results 71 to 80 of about 10,740 (91)

Immunoglobulin binding protein (BiP) forms two types of dimers

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract Immunoglobulin binding protein (BiP) is a chaperone protein that plays crucial roles in protein folding and transport by binding unfolded proteins in the substrate binding domain (SBD), an interaction allosterically linked to the nucleotide occupancy of the nucleotide binding domain (NBD).
Karina New   +6 more
wiley   +1 more source

Cementum Attachment Protein‐Derived Peptides Modulate Brushite and Calcium Oxalate Crystallization In Vitro

open access: yesJournal of Peptide Science, Volume 32, Issue 8, August 2026.
Cementum attachment protein‐derived peptides adsorb to specific crystallographic faces of brushite and calcium oxalate, blocking calcium deposition. This phosphorylation‐enhanced modulation alters crystal growth under conditions in vitro, leading to the formation of irregular brushite crystals and rosette‐like calcium oxalate morphologies.
Alberto Mimila‐Cortes   +9 more
wiley   +1 more source

Targeting RANKL Prevents Bone Loss, Improves Muscle Function and Extends Lifespan in Progeroid Mice

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
Targeting of RANKL by genetic and pharmacological approaches ameliorates key features of the progeroid phenotype in Zmpste24−/− mice. RANKL intervention restores bone mass, improves muscle phenotype, and extends survival. These findings support further exploration of RANKL‐targeted therapies for Hutchinson‐Gilford progeria syndrome.
Sandra Freitas‐Rodríguez   +11 more
wiley   +1 more source

Characterisation of the Mesial Root and Middle Mesial Canal Morphology in Mandibular First Molars: An Ex Vivo Micro‐CT Study

open access: yesAustralian Endodontic Journal, Volume 52, Issue 2, Page 364-380, August 2026.
ABSTRACT This ex vivo study characterised the mesial root morphology of mandibular first molars with a middle mesial canal (MMC) using micro‐CT. Among 469 scanned molars, 42 (8.96%) presented an MMC. Morphological parameters analysed included canal configuration, chamber orifice features, dentine thickness, isthmus type, and aspect ratio.
Nuno Rodrigues dos Santos   +3 more
wiley   +1 more source

Efeito da adição de aminoácidos essenciais à dieta sobre a secreção de enzimas digestivas de jundiá Rhamdia quelen (Siluriformes, Pimelodidae) = Effect of dietary essential amino acids addition on digestive enzime secretion in silver catfish Rhamdia quelen (Siluriformes, Pimelodidae)

open access: yesActa Scientiarum: Biological Sciences, 2009
Em estudos realizados com variação no teor de proteína na ração para peixes, foi demonstrado o aumento das atividades de protease alcalina, protease ácida, tripsina e quimiotripsina do trato digestório de jundiá (Rhamdia quelen).
Alexandre Bernardini Ungar   +3 more
doaj  

Thioredoxin system modulates metabolic and stomatal responses to elevated CO2 in Arabidopsis

open access: yesNew Phytologist, Volume 251, Issue 4, Page 1774-1791, August 2026.
Integrative model of extraplastidial NADPH‐dependent thioredoxin reductase/thioredoxin system‐mediated regulation of stomatal function, redox homeostasis, and metabolic responses under ambient and elevated CO2 in Arabidopsis thaliana. Summary The NADPH‐dependent thioredoxin reductase/thioredoxin (NTR/TRX) system plays a central role in maintaining ...
Paula da Fonseca‐Pereira   +11 more
wiley   +1 more source

Biochemical responses, blood gas, oxidative stress and lipid peroxidation of goats transfused with fresh or stored whole homologous blood

open access: yesPesquisa Veterinária Brasileira
: Blood transfusion is a therapeutic procedure of great importance for veterinary medicine, in spite of only few studies in the literature on hemotherapy in goats.
Nayanna B.S. Fonseca   +7 more
doaj   +1 more source

Lysine Biosynthesis Defines a Metabolic Checkpoint for Gibberellin‐Mediated Growth in Arabidopsis thaliana

open access: yesPlant, Cell &Environment, Volume 49, Issue 8, Page 5343-5357, August 2026.
ABSTRACT Lysine represents a metabolic hub linking mitochondrial energy status with amino acid catabolism, yet its role in coordinating plant growth and development remains poorly characterised. The dapat mutant, which is deficient in L,L‐diaminopimelate aminotransferase (DAPAT), exhibits severe growth inhibition associated with broad metabolic ...
Débora Gonçalves Gouveia   +10 more
wiley   +1 more source

Editorial

open access: yesMutis, 2014
En una publicación del 25 de julio de 2014 en la prestigiosa revista Plos Genetics, se propuso la siguiente hipótesis: “Un 99% del genoma humano no codifica proteínas, ¿cuánta de esta fracción no codificante de las secuencias de ADN tiene un papel ...
Javier Hernández Fernández
doaj  

Locally adapted Arabidopsis thaliana accessions show transcriptomic plasticity in a multi‐timescale analysis of whole‐genome gene expression in a natural environment

open access: yesPlant Biology, Volume 28, Issue 5, Page 1641-1656, August 2026.
Natural Arabidopsis thaliana accessions showed remarkable plasticity in both life‐cycle phenology and whole‐genome gene expression patterns in in natura field experiments. Nevertheless, local adaptation in fitness‐related life‐history traits can also be detected at the whole‐genome gene expression level.
A. Martínez‐Pérez   +8 more
wiley   +1 more source

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