Cytotoxicity of Esculetin Compared with Vinblastine and Paclitaxel in PC-3 Prostate Cancer Cells
Current OncologyBackground/Objectives: Metastatic prostate cancer is among the therapy-resistant human neoplasms. PC-3 is a commonly used experimental cell line that does not express androgen receptors.
Ana I. García-Pérez +4 more
doaj +1 more source
20 años del Servicio de Huellas Digitales Genéticas [breves] [PDF]
El Servicio de Huellas Digitales Genéticas de la Facultad de Farmacia y Bioquímica de la UBA celebró su 20º aniversario. Creado en 1991 fue y es el primer centro institucional en nuestro país dedicado a la Biología Molecular Forense.
core
La Universidad en el contexto internacional: Algunos aspectos comparativos [PDF]
, 2001 Roberto Marco Cuéllar: Doctor en Medicina y Ciencias. Profesor del Departamento de Bioquímica de la Facultad de Medicina de la Universidad Autónoma de Madrid desde 1969, Científico Titular del CSC desde 1970, y desde 1984 es Catedrático de Bioquímica ...
Marco Cuéllar, Roberto
core +1 more source
p53 Genetics and Biology in Lung Carcinomas: Insights, Implications and Clinical Applications
BiomedicinesThe TP53 gene is renowned as a tumor suppressor, playing a pivotal role in overseeing the cell cycle, apoptosis, and maintaining genomic stability. Dysregulation of p53 often contributes to the initiation and progression of various cancers, including ...
Dixan A. Benitez +7 more
doaj +1 more source
Thymine starvation causes abortive initiation of chromosome replication critical for cell death in Escherichia coli [PDF]
, 2013 Presentado en: XXXVI Congreso SEBBM (Sociedad Española de Bioquímica y Biología Molecular), Madrid, 4-6 septiembre, 2013Thymineless death (TLD), a phenomenon in which thymine auxotrophy becomes lethal when cells are starved for thymine, can be prevented
Guzmán Cabañas, Elena +2 more
core
Vascular Smooth Muscle Cell Migration and P70S6K: Key Players in Intimal Hyperplasia Development
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Vascular smooth muscle cell (VSMC) recruitment and activation by vessel injury cause intimal hyperplasia (IH) and restenosis. Drug‐eluting stents releasing mTOR (mechanistic target of rapamycin) blockers (sirolimus, everolimus [EV]) improve ...
Sara Moreno‐Estar +7 more
doaj +1 more source
Study of Transcriptional Regulatory Network Controlling Strawberry Fruit Ripening and Quality [PDF]
, 2018 Ponencia invitadaRipening is a critical step for the development of flavor quality in fruits. This character has significantly declined in many fleshy fruits over recent decades. This is particularly significant in strawberry (Fragaria × ananassa), where
Lucas-Reina, Eva +4 more
core
Antitumor and antiangiogenic potential of solomonamide synthesis intermediates [PDF]
, 2017 Es comunicación (formato panel) a congreso internacionalIn this work we developed a new synthetic strategy towards the solomonamides. a novel class of cyclopeptides of marine origin. The described synthetic approach utilized an olefin metathesis reaction
Carrillo Fernandez, Paloma +6 more
core
Deciphering Strawberry Ripening by Tissue Specific Gene Regulatory Networks [PDF]
, 2018 During ripening, fruits undergo a number of metabolic and physiological changes leading to softening and improvement of characters such as flavor and palatability.
Botella-Mesa, Miguel Angel +8 more
core