Insights into aging mechanisms from comparative genomics in orange and silver roughies
Scientific ReportsThe demersal fish orange roughy (Hoplostethus atlanticus) can live for up to 250 years, twenty times more than its congener silver roughy (Hoplostethus mediterraneus). Studies of Hoplostethus have focused mainly on its ecology and conservation due to its
Dido Carrero +5 more
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Changes in P2Y Purinergic Receptor Expression in the Ciliary Body in a Murine Model of Glaucoma
Frontiers in Pharmacology, 2017 Glaucoma is a neuropathology, often accompanied by an elevated intraocular pressure (IOP), which can lead to blindness. Since DBA/2J mice develop glaucoma, several studies of the physiopathology of glaucoma have been reported in this animal model.
Begoña Fonseca +5 more
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Estudio del mecanismo molecular del sistema de dos componentes TodS/TodT [PDF]
, 2008 Tesis Univ. Granada. Departamento de Bioquímica y Biología Molecular.
Busch, Andreas
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Uridine Prevents Negative Effects of OXPHOS Xenobiotics on Dopaminergic Neuronal Differentiation
Cells, 2019 Neuronal differentiation appears to be dependent on oxidative phosphorylation capacity. Several drugs inhibit oxidative phosphorylation and might be detrimental for neuronal differentiation.
Eldris Iglesias +8 more
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Caracterización molecular del extremo amino terminal de la proteina reguladora xyis [PDF]
, 2002 Universidad de Granada, Departamento de Bioquímica y Biología Molecular.
Ruiz Arroyo, Raquel
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Author Correction: Determination of the boundary lipids of sticholysins using tryptophan quenching
Scientific Reports, 2023 Juan Palacios‑Ortega +7 more
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Cytotoxicity of Esculetin Compared with Vinblastine and Paclitaxel in PC-3 Prostate Cancer Cells
Current OncologyBackground/Objectives: Metastatic prostate cancer is among the therapy-resistant human neoplasms. PC-3 is a commonly used experimental cell line that does not express androgen receptors.
Ana I. García-Pérez +4 more
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FEBS 1969: A Key Advance for Biochemistry in Spain [Vídeo]
, 2019 1 fichero .pdf con enlaces a las dos versiones del vídeo (español; inglés), de una duración de 3 min. 18 segs. Guión: I. Yruela; Imágenes: Archivo de la Sociedad Española de Bioquímica y Biología Molecular (SEBBM); Digitalización: URICI-CSIC ...
CSIC - Unidad de Recursos de Información Científica para la Investigación (URICI) +3 more
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p53 Genetics and Biology in Lung Carcinomas: Insights, Implications and Clinical Applications
BiomedicinesThe TP53 gene is renowned as a tumor suppressor, playing a pivotal role in overseeing the cell cycle, apoptosis, and maintaining genomic stability. Dysregulation of p53 often contributes to the initiation and progression of various cancers, including ...
Dixan A. Benitez +7 more
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Vascular Smooth Muscle Cell Migration and P70S6K: Key Players in Intimal Hyperplasia Development
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Vascular smooth muscle cell (VSMC) recruitment and activation by vessel injury cause intimal hyperplasia (IH) and restenosis. Drug‐eluting stents releasing mTOR (mechanistic target of rapamycin) blockers (sirolimus, everolimus [EV]) improve ...
Sara Moreno‐Estar +7 more
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