Results 71 to 80 of about 39,113 (232)

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

open access: yesInternational Journal of Cancer, Volume 159, Issue 2, Page 410-422, 15 July 2026.
What's new? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado   +54 more
wiley   +1 more source

The Role of Natriuretic peptides in Renovascular Hypertension and its correlation with the Evolution of Myocardial Hypertrophy [PDF]

open access: yes, 2010
The interactions between pressure and volume overload that occur in hypertension lead to different patterns of cardiac hypertrophy and to increase in natriuretic peptides (NPs).
Cavallero, Carmen Susana   +4 more
core  

Exposure to Gestational Intermittent Hypoxia Does Not Impair the Metabolic Function or Accelerate the Biological Ageing Process of Offspring of Either Sex

open access: yesJournal of Sleep Research, Volume 35, Issue 3, June 2026.
ABSTRACT Obstructive sleep apnea (OSA), marked by intermittent hypoxia, is associated with obesity, type 2 diabetes and metabolic associated fatty liver disease. In pregnancy, it remains underdiagnosed despite links to gestational diabetes, hypertension, and foetal growth restriction.
Esther Valverde‐Perez   +6 more
wiley   +1 more source

Targeted mutagenesis of FaTM6 in the Octoploid Strawberry (Fragaria x ananassa) using the CRISPR/Cas9 System [PDF]

open access: yes, 2018
The B-class of MADS-box transcription factors has been studied in many plant species, but remain functionally uncharacterized in the Rosaceae family.
Duarte-Conde, José Antonio   +2 more
core  

Promoter sequence of Shiga Toxin II (Stx2) is recognized in vivo leading to the production of biologically active Stx2 [PDF]

open access: yes, 2013
Shiga toxins (Stxs) are the main agent responsible for the development of hemolytic uremic syndrome (HUS), the most severe and life-threatening systemic complication of infection with enterohemorrhagic Escherichia coli (EHEC) strains.
Baez, Natalia Soledad   +10 more
core   +1 more source

Crystal structure and functional characterization of an Asp49 phospholipase A2 from the bushmaster (Lachesis muta)

open access: yesActa Crystallographica Section F, Volume 82, Issue 5, Page 150-159, May 2026.
The crystal structure of an Asp49 phospholipase A2 from L. muta is reported, revealing a tetrameric assembly, catalytic conservation and a polarized electrostatic surface potentially linked to membrane targeting.Snake‐venom phospholipases A2 (PLA2s) are small, structurally conserved enzymes that contribute significantly to the pathophysiology of ...
Noelia Erika Neyra Chama   +9 more
wiley   +1 more source

Glutamate synthases from conifers: gene structure and phylogenetic studies

open access: yesBMC Genomics, 2018
Background Plants synthesize glutamate from ammonium by the combined activity of the enzymes glutamine synthetase (GS) and glutamate synthase (GOGAT) through the glutamate synthase cycle.
Ángel García-Gutiérrez   +2 more
doaj   +1 more source

Protein dysfunction, activity and dysactivity: studies on the the papillomavirus E7 protein by means of reverse molecular biology [PDF]

open access: yes, 2015
Reviso algunos conceptos aplicados a las proteínas en investigaciones biológicas de distintas escalas, tomando como ejemplo a la proteína E7 del virus del papiloma.
Sánchez Miguel, Ignacio Enrique
core  

Foliculogénesis Ovárica en la Raya Marmorada, Sympterygia bonapartii (Müller & Henle, 1841) (Chondrichthyes, Rajidae) [PDF]

open access: yes, 2011
Los Condrictios se han convertido en un recurso económico importante en las últimas décadas, siendo Argentina uno de los países que más explota tiburones y rayas, incluso a niveles que exceden los límites de varias especies.
Díaz Andrade, María Constanza   +3 more
core   +1 more source

La enseñanza del metabolismo: retos y oportunidades [PDF]

open access: yes, 2017
En el marco del Proyecto de Innovación Educativa de la Universidad de Málaga PIE15-163, cuya descripción y resultados incluimos, decidimos que esta era una excelente oportunidad para reflexionar acerca de la enseñanza del metabolismo y de poner por ...
Aldana-Montes, Jose Francisco   +27 more
core   +1 more source

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