Results 51 to 60 of about 24,025,492 (170)

Modulation of Anaphase‐Promoting Complex Genes Regulates Root‐Knot Nematode Gall Development and Plant Susceptibility

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT The anaphase‐promoting complex/cyclosome (APC/C) is a multi‐subunit E3 ubiquitin ligase that regulates cell cycle progression, but its role in plant‐pathogen interactions is poorly understood. Here, we demonstrate that regulation of the ubiquitin–proteasome system, involving APC/C‐associated components, is critical for coordinating host cell ...
Aline Köhn Carneiro   +8 more
wiley   +1 more source

Caracterización bioquímica y molecular del sistema de dos componentes TODS/TODT de Pseudomonas putida DOT-T1E [PDF]

open access: yes, 2008
Capítulo 3: Resultados, escrito íntegramente en inglésTesis Univ. Granada. Departamento de Bioquímica y Biología Molecular I. Leída el 8 de abril de 2008Tesis en colaboración con el Consejo Superior de Investigaciones Científicas.
Lacal Romero, Jesús
core   +1 more source

Creating a Rat Model of Chronic Variate Stress

open access: yesBio-Protocol, 2014
Stress is a condition of human experience and an important factor in the onset of various diseases. There are numerous studies showing how stress can accelerate cell aging, immune senescence and some age-related diseases such as neurodegenerative ...
Rocío de Pablos   +2 more
doaj   +1 more source

The MexMAGIC population reveals the genetic architecture of traits exhibiting clinal variation in Mexican native maize

open access: yesNew Phytologist, Volume 252, Issue 3, Page 1296-1313, November 2026.
The MexMAGIC population mixes native maize varieties from across Mexico to study functional genetic diversity. Summary Defining the genetic basis of local adaptation is a key goal of evolutionary biology and crop improvement. Theory predicts that when selective pressures follow differences in the environment, a cline will be established.
Sergio Perez‐Limón   +18 more
wiley   +1 more source

Pseudociencias y medicina [PDF]

open access: yes, 2015
© SEBBM. Se autoriza la reproducción del contenido, siempre que se cite la procedencia.[ES] Los científicos tenemos la obligación moral de divulgar lo que hacemos y que la gente nos entienda. Hay mucho en juego, entre otras cosas, evitar que proliferen
Mulet, José Miguel
core  

AKT Phosphorylation of FOXK2 at Ser398 Impacts Breast Cancer Cell Growth and Viability

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Higher FOXK2 protein levels are associated with increased AKT phosphorylation and chemoresistance in breast cancer cells. AKT modulates FOXK2 protein levels, with no such regulation in FOXK2 mRNA levels. GSK3β, a known substrate of AKT (dotted arrow), does not regulate FOXK2 in our cellular model.
L. T. Carneiro   +10 more
wiley   +1 more source

Life‐History, Stress‐Resistance, and Transcriptomic Variation Among a Mexican Caenorhabditis elegans Isolate and Contemporary and Ancestral N2 Lineages

open access: yesEcology and Evolution, Volume 16, Issue 10, October 2026.
We compared a recently isolated wild strain of Caenorhabditis elegans from Mexico City (VJV2) with the contemporary standard N2 Lab strain and the cryopreserved N2 Ancestral lineage. The strains differed in lifespan, fertility, and survival under pathogen, oxidative, and heat stress.
Jaqueline Hersch‐González   +6 more
wiley   +1 more source

Integrated Metabolomic and Bioenergetic Profiling Reveals Axl as a Key Regulator of Macrophage Homeostasis

open access: yesEuropean Journal of Immunology, Volume 56, Issue 10, October 2026.
Axl deficiency disrupts peritoneal macrophage identity and function, impairing glycolysis, TCA metabolism, and mitochondrial respiration while weakening antioxidant defenses. This coordinated metabolic and redox collapse extends systemically, highlighting Axl as a key regulator of immunometabolic homeostasis.
Jesuino R M Ferreira   +15 more
wiley   +1 more source

General regulatory factors exert differential effects on nucleosome sliding activity of the ISW1a complex

open access: yesBiological Research
Background Chromatin dynamics is deeply involved in processes that require access to DNA, such as transcriptional regulation. Among the factors involved in chromatin dynamics at gene regulatory regions are general regulatory factors (GRFs). These factors
Andrea Oyarzún-Cisterna   +6 more
doaj   +1 more source

Determinants of Abl kinase stability and drug binding thermodynamics: Role of regulatory domains and phosphorylation

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract Activity dysregulation of Abl kinase is the primary cause for chronic myeloid leukemia (CML). Despite extensive characterization, the thermodynamic basis of Abl stability and inhibitor recognition remains incompletely understood. To characterize the cooperative folding organization of Abl and the communication between its structural units, we ...
Alan Juárez‐Barragán   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy