Results 51 to 60 of about 39,113 (232)

Deletion of C3G in hepatocytes impairs full liver maturation and alters glucose homeostasis

open access: yesCell Death and Disease
C3G (RapGEF1) regulates the biology of liver hepatic progenitor cells and hepatocarcinoma cells, but its role in hepatocytes remained unknown. Therefore, we generated a mouse model lacking C3G in hepatocytes (C3GKOAlb), which showed liver damage as ...
Nerea Palao   +11 more
doaj   +1 more source

Aryl Hydrocarbon Receptor: From Homeostasis to Tumor Progression

open access: yesFrontiers in Cell and Developmental Biology, 2022
Transcription factor aryl hydrocarbon receptor (AHR) has emerged as one of the main regulators involved both in different homeostatic cell functions and tumor progression.
Claudia Rejano-Gordillo   +5 more
doaj   +1 more source

Proyecto botánica forense: las ciencias agronómicas más allá de la agronomía. [PDF]

open access: yes, 2015
La botánica forense es una ciencia compleja que aplica la botánica a las investigaciones policiales. Su papel principal en una investigación reside en fundamentar las relaciones entre la evidencia de origen vegetal y un delito.

core  

Plasmatic Biochemical Variables Associated with Polymorphisms in the Endothelin-1 and Endothelin-1 Receptor a Genes in Hypertensive Patients: Pilot Study [PDF]

open access: yes, 2016
Endothelin-1 (ET-1) is a potent vasoconstrictive peptide, and its activity is mediated by thetype A receptor (EDNRA). This action may play a significant role in the etiology of hypertension.There are different works that shows an association between ...
Bertolotto, Patricia Isolina   +7 more
core   +2 more sources

Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol   +6 more
wiley   +1 more source

Back to the future: Transplanting the chloroplast TrxF–FBPase–SBPase redox system to cyanobacteria

open access: yesFrontiers in Plant Science, 2022
Fructose-1,6-bisphosphatase (FBPase) and sedoheptulose-1,7-bisphosphatase (SBPase) are two essential activities in the Calvin–Benson–Bassham cycle that catalyze two irreversible reactions and are key for proper regulation and functioning of the cycle ...
Raquel García-Cañas   +5 more
doaj   +1 more source

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

open access: yesThe FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira   +16 more
wiley   +1 more source

Creating a Rat Model of Chronic Variate Stress

open access: yesBio-Protocol, 2014
Stress is a condition of human experience and an important factor in the onset of various diseases. There are numerous studies showing how stress can accelerate cell aging, immune senescence and some age-related diseases such as neurodegenerative ...
Rocío de Pablos   +2 more
doaj   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

La cepa letal de la E. coli [PDF]

open access: yes, 2011
La crisis alimentaria alemana tiene una sola protagonista: la cepa O104 de la bacteria Escherichia coli. El catedrático de Bioquímica y Biología Molecular de la Universidad Politécnica de Madrid, Francisco García Olmedo, autor de El ingenio y el hambre ...
García Olmedo, Francisco
core   +1 more source

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