Results 51 to 60 of about 24,025,492 (170)
ABSTRACT The anaphase‐promoting complex/cyclosome (APC/C) is a multi‐subunit E3 ubiquitin ligase that regulates cell cycle progression, but its role in plant‐pathogen interactions is poorly understood. Here, we demonstrate that regulation of the ubiquitin–proteasome system, involving APC/C‐associated components, is critical for coordinating host cell ...
Aline Köhn Carneiro +8 more
wiley +1 more source
Caracterización bioquímica y molecular del sistema de dos componentes TODS/TODT de Pseudomonas putida DOT-T1E [PDF]
Capítulo 3: Resultados, escrito íntegramente en inglésTesis Univ. Granada. Departamento de Bioquímica y Biología Molecular I. Leída el 8 de abril de 2008Tesis en colaboración con el Consejo Superior de Investigaciones Científicas.
Lacal Romero, Jesús
core +1 more source
Creating a Rat Model of Chronic Variate Stress
Stress is a condition of human experience and an important factor in the onset of various diseases. There are numerous studies showing how stress can accelerate cell aging, immune senescence and some age-related diseases such as neurodegenerative ...
Rocío de Pablos +2 more
doaj +1 more source
The MexMAGIC population mixes native maize varieties from across Mexico to study functional genetic diversity. Summary Defining the genetic basis of local adaptation is a key goal of evolutionary biology and crop improvement. Theory predicts that when selective pressures follow differences in the environment, a cline will be established.
Sergio Perez‐Limón +18 more
wiley +1 more source
Pseudociencias y medicina [PDF]
© SEBBM. Se autoriza la reproducción del contenido, siempre que se cite la procedencia.[ES] Los científicos tenemos la obligación moral de divulgar lo que hacemos y que la gente nos entienda. Hay mucho en juego, entre otras cosas, evitar que proliferen
Mulet, José Miguel
core
AKT Phosphorylation of FOXK2 at Ser398 Impacts Breast Cancer Cell Growth and Viability
Higher FOXK2 protein levels are associated with increased AKT phosphorylation and chemoresistance in breast cancer cells. AKT modulates FOXK2 protein levels, with no such regulation in FOXK2 mRNA levels. GSK3β, a known substrate of AKT (dotted arrow), does not regulate FOXK2 in our cellular model.
L. T. Carneiro +10 more
wiley +1 more source
We compared a recently isolated wild strain of Caenorhabditis elegans from Mexico City (VJV2) with the contemporary standard N2 Lab strain and the cryopreserved N2 Ancestral lineage. The strains differed in lifespan, fertility, and survival under pathogen, oxidative, and heat stress.
Jaqueline Hersch‐González +6 more
wiley +1 more source
Axl deficiency disrupts peritoneal macrophage identity and function, impairing glycolysis, TCA metabolism, and mitochondrial respiration while weakening antioxidant defenses. This coordinated metabolic and redox collapse extends systemically, highlighting Axl as a key regulator of immunometabolic homeostasis.
Jesuino R M Ferreira +15 more
wiley +1 more source
Background Chromatin dynamics is deeply involved in processes that require access to DNA, such as transcriptional regulation. Among the factors involved in chromatin dynamics at gene regulatory regions are general regulatory factors (GRFs). These factors
Andrea Oyarzún-Cisterna +6 more
doaj +1 more source
Abstract Activity dysregulation of Abl kinase is the primary cause for chronic myeloid leukemia (CML). Despite extensive characterization, the thermodynamic basis of Abl stability and inhibitor recognition remains incompletely understood. To characterize the cooperative folding organization of Abl and the communication between its structural units, we ...
Alan Juárez‐Barragán +5 more
wiley +1 more source

