Results 31 to 40 of about 39,113 (232)

Xenobiotics that affect oxidative phosphorylation alter differentiation of human adipose-derived stem cells at concentrations that are found in human blood

Disease Models & Mechanisms, 2015
Adipogenesis is accompanied by differentiation of adipose tissue-derived stem cells to adipocytes. As part of this differentiation, biogenesis of the oxidative phosphorylation system occurs.
Laura Llobet, Janne M. Toivonen, Julio Montoya, Eduardo Ruiz-Pesini, Ester López-Gallardo   +4 more
doaj   +1 more source

Herramientas de comunicación en el aprendizaje de la Bioquímica [PDF]

, 2017
Sección Deptal. de Bioquímica y Biología Molecular (Biológicas)Depto. de Bioquímica y Biología MolecularFac. de Ciencias BiológicasFac.
Aragonés Sanz, María Dolores, Gómez Miguel, Begoña, Martínez Díaz, Ana, Megías Fresno, Alicia, Oñaderra Sanchez, Mercedes, Portolés Pérez, María Teresa   +5 more
core   +1 more source

Environmental hyperosmolality regulates phospholipid biosynthesis in the renal epithelial cell line MDCK [PDF]

, 2013
Hyperosmolality is a key signal for renal physiology. On the one hand, it contributes to the differentiation of renal medullary structures and to the development of the urinary concentrating mechanism. On the other, it is a stress factor.
Casali, Cecilia Irene, Favale, Nicolas Octavio, Fernandez, Maria del Carmen, Weber, Karen   +3 more
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Molecular and functional characterization of ferredoxin NADP(H) oxidoreductase from Gracilaria chilensis and its complex with ferredoxin

Biological Research, 2017
Backgroud Ferredoxin NADP(H) oxidoreductases (EC 1.18.1.2) (FNR) are flavoenzymes present in photosynthetic organisms; they are relevant for the production of reduced donors to redox reactions, i.e.
María Alejandra Vorphal, Carola Bruna, Traudy Wandersleben, Jorge Dagnino-Leone, Francisco Lobos-González, Elena Uribe, José Martínez-Oyanedel, Marta Bunster   +7 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Epitranscriptome changes triggered by ammonium nutrition regulate the proteome response of maritime pine roots

Frontiers in Plant Science, 2022
Epitranscriptome constitutes a gene expression checkpoint in all living organisms. Nitrogen is an essential element for plant growth and development that influences gene expression at different levels such as epigenome, transcriptome, proteome, and ...
Francisco Ortigosa, César Lobato-Fernández, Juan Antonio Pérez-Claros, Francisco R. Cantón, Concepción Ávila, Francisco M. Cánovas, Rafael A. Cañas   +6 more
doaj   +1 more source

Bioquímica y biología molecular de las plantas [PDF]

, 2004
Si aplicamos un criterio antropocéntrico, las plantas superiores deben seguir de modo inmediato al hombre como objetos de interés tecnocientífico, ya que directa o indirectamente constituyen su principal sustento. Por otra parte, su papel central en la
García Olmedo, Francisco
core   +1 more source

Cytokine Production but Lack of Proliferation in Peripheral Blood Mononuclear Cells from Chronic Chagas' Disease Cardiomyopathy Patients in Response to T. cruzi Ribosomal P Proteins [PDF]

, 2014
Background:Trypanosoma cruzi ribosomal P proteins, P2β and P0, induce high levels of antibodies in patients with chronic Chagas' disease Cardiomyopathy (CCC).
A Moncayo, A Rassi Jr, AC Arnholdt, Alcinette Buying, ARL Teixeira, AS de Melo, Augusto Atienza, B Zingales, C Aznar, C Chen, C Junqueira, C Smulski, Carlos A. Buscaglia, Clemencia Pinilla, CR De Marchi, E Cunha-Neto, E Mahler, E Mahler, E Olivares Fontt, E Olivares Fontt, E Roffê, EA Mesri, EB Gomez, F Kierszenbaum, F Nagajyothi, GE Cánepa, Graciela Perez Prados, GV Levy, I Ferrari, J Scharfstein, J Zhu, JA Fiuza, JAS Gomes, JC Coura, JM Burgos, JM Di Noia, JR Coura, K Elkon, Karina A. Gómez, KM Bonney, Laura M. Tasso, LC Abel, M Juri Ayub, M Ribeirao, MA Zacks, Mauricio Martins Rodrigues, MB Rosenbaum, MJ Morato, MV Elizari, NA Giraldo, P Lopez Bergami, P Lopez-Bergami, PA Chiale, Pablo Chiale, Radleigh Santos, RCG Fares, Ricardo Bonato, S Brandariz, S de Barros-Mazon, S Muller, Silvia A. Longhi, SL Topalian, V Judkowski, V Michailowsky, V Schultena, Valeria A. Judkowski, Virginia Balouz, VMB Lorena, WO Dutra, WO Dutra, WO Dutra, WO Dutra, WR Cuna, Y Belkaid, Y Morán-Utrera, Y Shi   +75 more
core   +4 more sources

Stereochemical Modulation of Palladacyclopentadienyl Complexes Bearing Diphosphine Ligands: A Key to Enhanced DNA Interaction and Anticancer Activity

European Journal of Inorganic Chemistry, EarlyView.
A modular library of structurally robust palladacyclopentadienyl Pd(II) complexes bearing achiral and chiral diphosphines was developed, revealing a strong influence of diphosphine design and ligand chirality on cytotoxicity and selectivity against ovarian cancer cells, including platinum‐resistant models.
Stefania Mautone, Martina Scianna, Isabella Caligiuri, Laura Orian, Pablo Nogara, Nicola Demitri, Flavio Rizzolio, Thomas Scattolin   +7 more
wiley   +1 more source