Results 31 to 40 of about 24,025,492 (170)

Epitranscriptome changes triggered by ammonium nutrition regulate the proteome response of maritime pine roots

Frontiers in Plant Science, 2022
Epitranscriptome constitutes a gene expression checkpoint in all living organisms. Nitrogen is an essential element for plant growth and development that influences gene expression at different levels such as epigenome, transcriptome, proteome, and ...
Francisco Ortigosa, César Lobato-Fernández, Juan Antonio Pérez-Claros, Francisco R. Cantón, Concepción Ávila, Francisco M. Cánovas, Rafael A. Cañas   +6 more
doaj   +1 more source

Biological Effects of Selenium‐Containing Ionic Liquids: Cytotoxicity, Mercury Interaction, and Antiproliferative Activity in Glioblastoma Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium‐containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids.
Guilherme Schmitt Rieder, Alessandro de Souza Prestes, Fernanda D'Avila da Silva, Nilda de Vargas Barbosa, Alix Y. Bastidas Ángel, Mariana F. Soares, Carolina Martins Fernandes, Maria Anttônia Oliveira Petersen, Manuela Moura Silva, Juliete Nathali Scholl, Fabrício Figueiró, Pablo Andrei Nogara, Laura Orian, Eduardo E. Alberto, Michael Aschner, Diogo Onofre Gomes de Souza, Debora Guerini de Souza, João Batista Teixeira da Rocha   +17 more
wiley   +1 more source

Nacimiento y evolución de la bioquímica y la biología molecular en la Comunidad Valenciana (1963-2013) [PDF]

, 2013
Carbonell Gisbert, J. (2013). Nacimiento y evolución de la bioquímica y la biología molecular en la Comunidad Valenciana (1963-2013). SEBBM. Revista de la Sociedad Española de Bioquímica y Biología Molecular. 178:36-38. https://riunet.upv.es/handle/10251/
CARBONELL GISBERT, JUAN
core  

Clinical and molecular characterization of a novel pathogenic AIFM1 E336K mutation connecting mitochondrial dysfunction and neurodegeneration

Cell Communication and Signaling
Mutations in the AIFM1 gene, encoding the apoptosis-inducing factor (AIF), have been associated with a spectrum of neurometabolic disorders. However, the mechanistic basis underlying their pathogenicity remains poorly understood.
Miguel Ferrer, María Pedrón, Olga Soriano, Marta Martínez-Julvez, Mikel Marín-Baquero, Rut García-Villanueva, Adrián Velázquez-Campoy, Joaquín Marco-Brualla, Cristina Ripollés-Yuba, Patricio Fernández-Silva, Milagros Medina, María Dolores Miramar, María Bestué, Raquel Moreno-Loshuertos, Patricia Ferreira   +14 more
doaj   +1 more source

Xenobiotics that affect oxidative phosphorylation alter differentiation of human adipose-derived stem cells at concentrations that are found in human blood

Disease Models & Mechanisms, 2015
Adipogenesis is accompanied by differentiation of adipose tissue-derived stem cells to adipocytes. As part of this differentiation, biogenesis of the oxidative phosphorylation system occurs.
Laura Llobet, Janne M. Toivonen, Julio Montoya, Eduardo Ruiz-Pesini, Ester López-Gallardo   +4 more
doaj   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

Biotecnología agrícola para mejorar la tolerancia a sequía y salinidad [PDF]

, 2016
Rodríguez Egea, PL.; Pardo Muñoz, JM. (2016). Biotecnología agrícola para mejorar la tolerancia a sequía y salinidad. SEBBM. Revista de la Sociedad Española de Bioquímica y Biología Molecular. 188:21-24.
Rodríguez Egea, Pedro Luís, Pardo Muñoz, José Manuel   +1 more
core  

FARFOOD: a database of potential interactions between food compounds and drugs

BioData Mining
Nutrition is a fundamental aspect in human life development, both from a socio-economic and medical perspective. In recent years, new personalized approaches have been added to the biochemical study of nutrients. These approaches consider both the effect
Ana María Nevado-Bulnes, Dixan Agustin Benitez, Guadalupe Cumplido-Laso, Jose María Carvajal-González, Sonia Mulero-Navarro, Angel-Carlos Román   +5 more
doaj   +1 more source

Neuroinflammation alters cellular proteostasis by producing endoplasmic reticulum stress, autophagy activation and disrupting ERAD activation

Scientific Reports, 2017
Proteostasis alteration and neuroinflammation are typical features of normal aging. We have previously shown that neuroinflammation alters cellular proteostasis through immunoproteasome induction, leading to a transient decrease of proteasome activity ...
Cristina Pintado, Sandra Macías, Helena Domínguez-Martín, Angélica Castaño, Diego Ruano   +4 more
doaj   +1 more source

The Sponge-Derived Brominated Compound Aeroplysinin-1 Impairs the Endothelial Inflammatory Response through Inhibition of the NF-κB Pathway

Marine Drugs, 2022
(+)-Aeroplysinin-1 (Apl-1) is a brominated compound isolated from the marine sponge Aplysina aerophoba that exhibits pleiotropic bioactive effects, impairing cell growth in cancer cells, inhibiting angiogenesis in vitro and in vivo and modulating the ...
Isabel Vidal, Laura Castilla, Ana Dácil Marrero, Inés Bravo-Ruiz, Manuel Bernal, Inmaculada Manrique, Ana R. Quesada, Miguel Ángel Medina, Beatriz Martínez-Poveda   +8 more
doaj   +1 more source