Results 231 to 240 of about 58,775 (305)

Stirred tank bioreactor process for chikungunya vaccine candidate VEEV-ΔC-CHIKV. [PDF]

PLoS One
Chang T, Deng C, Xie L, Zheng Y, Zhang Y, Liu J, Fu Z, Zhang B, An Q, Tian D.   +9 more
europepmc   +1 more source

Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal, Christina Chan, S Patrick Walton   +2 more
wiley   +1 more source

Scaling the manufacture of adipose tissue-derived mesenchymal stromal cells: integrated bioreactor workflows from inoculation to harvest without the need of seed train. [PDF]

BMC Biotechnol
Costa MHG, Terrasso AP, Crespo IE, Valero R, Menéndez B, Painho B, Sousa CD, Gamelas B, Tomás H, Mancheno-Corvo P, Menta R, Gugel CR, Fernández-Gómez V, Herrero-Méndez Á, Mármol IZ, Avivar-Valderas A, Pérez LM, Rosa O, Lombardo E, Serra M, Ortiz-Virumbrales M.   +20 more
europepmc   +1 more source

Balancing Prediction Performance and Spectral Interpretability: Multimetric Guided Design of Raman Spectrum Preprocessing Pipelines to Transfer Single Compound Models to Bioprocess Data

Journal of Raman Spectroscopy, EarlyView.
Calibration models were trained using single‐compound Raman spectra of ethanol and glucose, and then transferred to bioprocess spectra. Preprocessing, optimized to meet a multimetric quality framework, enabled this transfer whilst preserving the characteristic bands and the chemical interpretability of the models.
Gianmarco Luchetti Sfondalmondo, Marieke E. Klijn   +1 more
wiley   +1 more source

MyBioScope: a new frontier in gut microbiome and health research. [PDF]

Bioresour Bioprocess
Žukauskaitė K, Horvath A, Tripolt S, Habisch H, Madl T, Pacher-Deutsch C, Nepel M, Balazs I, Stadlbauer V.   +8 more
europepmc   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure-Driven Non-Planar Membrane Deformation in a Bioreactor System. [PDF]

Adv Sci (Weinh)
Mansoor H, Juul G, Patel J, Pradhan H, Hepner G, Jewell J, Bardin M, Slusser R, Glezer A, Klouda L, Tanyeri M, Saraf A.   +11 more
europepmc   +1 more source

Challenges and knowledge gaps in corrosion and materials degradation of bioreactors for waste feedstocks. [PDF]

Discov Mater
Ramos-Suarez M, Zhang Y, Wharton J, Heaven S.   +3 more
europepmc   +1 more source

Computational fluid dynamics enables predictable scale-up of perfusion bioreactors for microvessel production. [PDF]

PNAS Nexus
Vatani P, Suthiwanich K, Han Z, Romero DA, Nunes SS, Amon CH.   +5 more
europepmc   +1 more source

Solvent-Selective Complexity Reduction of Effluent Dissolved Organic Matter for ¹H NMR Spectroscopy. [PDF]

Anal Chem
Shakeri Yekta S, Enrich Prast A, Hedenström M, Sparrman T, Šafarič L, Carraro G, Oliveira HR, Anacleto TM, Björn A, Hertkorn N.   +9 more
europepmc   +1 more source

Microbioreactor design for eukaryotic cell-based biomedical applications. [PDF]

Front Bioeng Biotechnol
Rosero G, Pérez-Sosa C, Peñaherrera JP, Peñaherrera-Pazmiño AB.   +3 more
europepmc   +1 more source