Results 1 to 10 of about 14,895,724 (242)
Stem cells, cancer, and cancer stem cells [PDF]
Nature, 2001 Stem cell biology has come of age. Unequivocal proof that stem cells exist in the haematopoietic system has given way to the prospective isolation of several tissue-specific stem and progenitor cells, the initial delineation of their properties and expressed genetic programmes, and the beginnings of their utility in regenerative medicine.
T. Reya +3 more
semanticscholar +4 more sources
Plastic and Reconstructive Surgery, 2010 Stem cells are self-renewing cells capable of differentiating into multiple cell lines and are classified according to their origin and their ability to differentiate. Enormous potential exists in use of stem cells for regenerative medicine. To produce effective stem cell-based treatments for a range of diseases, an improved understanding of stem cell ...
Björn, Behr +4 more
openaire +5 more sources
Cells, Stem Cells, and Cancer Stem Cells [PDF]
Seminars in Reproductive Medicine, 2013 The stem cell field owes a great deal to the previous work conducted by embryologists and researchers devoted to reproductive medicine. The time is coming when this emerging field will pay off in the reproductive sciences by offering new avenues of understanding gametogenesis and early embryonic development.
Aguilar-Gallardo, C, Simon, C
openaire +4 more sources
Cell, 2006 Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about factors that induce this reprogramming.
Kazutoshi Takahashi, S. Yamanaka
semanticscholar +1 more source
Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. [PDF]
, 2017 Implanted biomaterials and biomedical devices generally induce foreign body reaction and end up with encapsulation by a dense avascular fibrous layer enriched in extracellular matrix.
Chu, Julia +9 more
core +2 more sources
Transient PP2A inhibition alleviates normal tissue stem cell susceptibility to cell death during radiotherapy [PDF]
, 2018 Unintended outcomes of cancer therapy include ionizing radiation (IR)-induced stem cell depletion, diminished regenerative capacity, and accelerated aging.
Fabbrizi, Maria Rita +6 more
core +3 more sources
The epithelial-mesenchymal transition generates cells with properties of stem cells.
Cell, 2008 The epithelial-mesenchymal transition (EMT) is a key developmental program that is often activated during cancer invasion and metastasis. We here report that the induction of an EMT in immortalized human mammary epithelial cells (HMLEs) results in the ...
Sendurai A Mani +14 more
semanticscholar +1 more source
Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil [PDF]
, 2018 Purpose of Review: This review summarizes the role of hypoxia and hypoxia-inducible factors (HIFs) in the regulation of stem cell biology, specifically focusing on maintenance, differentiation, and stress responses in the context of several stem cell ...
Aljoufi, Arafat +3 more
core +1 more source
Stem cells of Hydra magnipapillata can differentiate into somatic cells and germ line cells [PDF]
, 1987 We investigated whether all stem cells of Hydra can differentiate both somatic cells and gametes or if a separate germ line exists in these phylogenetically old organisms.
Bode +28 more
core +1 more source
The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development [PDF]
, 2015 Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem ...
Anna eNoble +9 more
core +2 more sources