Results 231 to 240 of about 9,750,247 (318)

Complete genome sequence of Oscillospiraceae bacterium MB24-C1, isolated from sewage sludge. [PDF]

Microbiol Resour Announc
Zhao J, Qiu W, Li F, Dong G, Li Y, Shih C-J, Wu Y-C, Wu C-H, Lai S-J, Xiao W, Zhang W-L, Li N, Chen S-C.   +12 more
europepmc   +1 more source

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, Volume 13, Issue 49, 3 September 2026.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

Role of pain and anxiety in mediating relationships between donation history and vasovagal reaction symptoms in blood donors in England. [PDF]

Transfusion
Wu Y, Di Angelantonio E, Kaptoge S, Wood AM, Gilchrist PT, Walker M, Kingston N, Masser B, Roberts D, Ferguson E, Kim LG.   +10 more
europepmc   +1 more source

CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen, Xiaoyun Luo, Huixin Gao, Yujing Ke, Yu Zhan, Xiaoting Xu, Xiaoxiao Xiong, Fengjiao Wei, Si Yang, Zhonghua Liu, Bolan Yu, Zhaofeng Huang, Yingjie Bian   +12 more
wiley   +1 more source

Genetic landscape of adult executive function reveals a cell-type-specific developmental origin. [PDF]

Nat Commun
Rahman MS, Frkatović-Hodžić A, van den Ameele J, Hill SM, Kingston N, Bradley JR, Tom BDM, Chinnery PF.   +7 more
europepmc   +1 more source

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

Emerging Multi-Source Transmission of SFTS Virus on a Remote Japanese Island: A One-Health Perspective. [PDF]

Int J Mol Sci
Oshiro R, Ihara M, Ibrahim CHO, Matsui K, Dalouny X, Pham Vu NH, Kurashige T, Xu Q, Hu S, Ngwe Tun MM, Takaki Y, Ogushi H, Setoguchi D, Katsuoka S, Murakami T, Matsumoto C, Hattori M, Hattori N, Miyamoto S, Sakai Y, Suzuki T, Yamanashi H, Murota H, Maeda T, Morita K, Yoshikawa A, Takamatsu Y.   +26 more
europepmc   +1 more source

A Modular PLUG‐IN Photosynthetic Chassis With Tunable Thermal Control for Mammalian Systems

Advanced Science, Volume 13, Issue 50, 7 September 2026.
This work establishes a “plug‐in” chassis compatible with mammalian systems that synchronizes growth, production, and cell‐wall re‐configuration, providing a versatile platform for photosynthetic bioproduction and microalgal synthetic biology. ABSTRACT Microalgae are promising photosynthetic platforms for high‐value compounds, yet their industrial use ...
Qinhua Gan, Zheng Li, Yunfei Chen, Mingting Du, Qianyi Wu, Congcong Miao, Tao Xu, Shan Wu, Xitao Chen, Xingwei Huang, Yuhui Cheng, Chengcheng Li, Yi Xin, Yandu Lu   +13 more
wiley   +1 more source

Dengue virus serotype 4-leading serotype epidemic and its clinical and molecular characteristics in Vung Tau, South Vietnam, 2020-2021. [PDF]

Trop Med Health
Nguyen NTT, Takemura T, Ihara M, Yamasato K, Kurashige T, Abe H, Tran HT, Vu H, Pham AHQ, Vu HTB, Nguyen LN, Pham HTT, Pham QD, Le TTH, Nguyen TTT, Hoang PVM, Nguyen HLK, Lam TT, Tran TT, Le LT, Vu KH, Chu TH, Ngwe Tun MM, Morita K, Takamatsu Y, Hasebe F, Le MTQ.   +26 more
europepmc   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, Volume 13, Issue 51, 14 September 2026.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source