Results 71 to 80 of about 7,502,466 (284)

Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling

Advanced Science, EarlyView.
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha, Di Feng, Ziru Xue, Zhiying Liu, Xiaochen Lin, Zhe Wang, Ling Xu, Jasper Fuk Woo Chan, Martin Cheung, Michael Shing Yan Huen, Yusong Guo, Kui Ming Chan, Yun Liu, Bo Gao   +13 more
wiley   +1 more source

Study and practical use of bioresources of citrus crops collection

Agrarian Scientific Journal
The article analyzes the collection of citrus crops of the Federal Research Center "Subtropical Scientific Center of the Russian Academy of Sciences" (FITC SNC RAS) in Sochi. The bioresource collection is kept alive in the field and in a container culture for varieties; the collection is represented by the genetic and ecological-geographical diversity ...
Raisa Vasilievna Kulyan, Aleksandr Sergeevich Kuleshov   +1 more
openaire   +1 more source

Methodical aspects of studying of bioresource collections of rare and economic valuable plants

Horticulture and viticulture, 2018
A full range of classical and modern methods of evaluation of biological peculiarities and economic characteristics of samples including in the bioresource collection is presented. The main directions of their study: seasonal development, ontomorphogenesis, reproductive biology and genetic certi fi cation.
O. Yu. Vasilyeva, O. V. Dorogina, I. N. Kuban, I. Ya. Sarlaeva, L. V. Buglova   +4 more
openaire   +1 more source

Collection, preservation and distribution of <i>Oryza</i> genetic resources by the National Bioresource Project RICE (NBRP-RICE)

Breeding Science, 2021
Biological resources are the basic infrastructure of bioscience research. Rice (Oryza sativa L.) is a good experimental model for research in cereal crops and monocots and includes important genetic materials used in breeding. The availability of genetic materials, including mutants, is important for rice research.
Sato, Yutaka, Tsuda, Katsutoshi, Yamagata, Yoshiyuki, Matsusaka, Hiroaki, Kajiya-Kanegae, Hiromi, Yoshida, Yuri, Agata, Ayumi, Ta, Kim Nhung, Shimizu-Sato, Sae, Suzuki, Toshiya, Nosaka-Takahashi, Misuzu, Kubo, Takahiko, Kawamoto, Shoko, Nonomura, Ken-Ichi, Yasui, Hideshi, Kumamaru, Toshihiro   +15 more
openaire   +3 more sources

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

ANALYSIS OF BIORESOURCE COLLECTIONS BY CLIMATIC RHYTHMS AND PHENOLOGICAL PROCESSES [PDF]

Успехи современного естествознания (Advances in Current Natural Sciences), 2021
A.V. Semenyutina, A.Sh. Huzhahmetova, A.A. Dolgih, V.A. Semenyutina, M.V. Tsoy   +4 more
openaire   +1 more source

MesobanK UK: an international mesothelioma bioresource. [PDF]

, 2015
Malignant pleural mesothelioma causes the greatest societal burden of all the asbestos-related diseases. Progress in better understanding tumour biology will be facilitated by the availability of quality-assured annotated tissue.
Rintoul, Robert C, MesobanK collaborators, Gittins, Jacki, Tabi, Zsuzsanna, Rassl, Doris M, Marciniak, Stefan J   +5 more
core   +2 more sources

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

Advanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou, Kristine J. Fernandez, Min Li Huang, Ewan K. A. Millar, Claire Vennin, Leila Eshraghi, Tan Dat Timothy Lam, Victoria Lee, Nyah C. Brooks, Janett Stoehr, Cristian Guaman Mendez, Douglas Strathdee, David Stevenson, David Herrmann, Sandra O'Toole, Paul Timpson, Max Nobis, C. Elizabeth Caldon   +17 more
wiley   +1 more source

Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank

Journal of Biomedical Science, 2020
Background The Taiwan Human Disease iPSC Service Consortium was established to accelerate Taiwan’s growing stem cell research initiatives and provide a platform for researchers interested in utilizing induced pluripotent stem cell (iPSC) technology.
Ching-Ying Huang, Ling-Hui Li, Wan-Tseng Hsu, Yu-Che Cheng, Martin W. Nicholson, Chun-Lin Liu, Chien-Yu Ting, Hui-Wen Ko, Shih-Han Syu, Cheng-Hao Wen, Zhuge Yan, Hsiang-Po Huang, Hong-Lin Su, Po-Min Chiang, Chia-Ning Shen, Hsin-Fu Chen, B. Lin Ju Yen, Huai-En Lu, Shiaw-Min Hwang, Shih-Hwa Chiou, Hong-Nerng Ho, Jer-Yuarn Wu, Timothy J. Kamp, Joseph C. Wu, Patrick C. H. Hsieh   +24 more
doaj   +1 more source