Results 161 to 170 of about 132,140 (253)

Andes virus reaches Europe: a narrative review on clinical challenges, diagnostic gaps and public health preparedness, 2026. [PDF]

Euro Surveill
Sberna G, Pályi B, Sondén K, Specchiarello E, Pettke A, de Melo GD, Meschi S, Carletti F, Daniel C, Kis Z, Bourhy H, Maggi F, Aarum J, Klingström J, Colavita F.   +14 more
europepmc   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Strengthening global biosecurity for synthetic nucleic acid technology: from sequence screening to risk-based governance in the AI era. [PDF]

Front Bioeng Biotechnol
Kato SE, Ndudzo A, Bayiga SO, Brenda N, Serwaa C, Baluku E, Mang'anda H, Peter JJ, Shamirah K, Perez M, Tawiah RN, Anguzu S, Malemia S.   +12 more
europepmc   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

Advanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang, Zifan Yang, Rong Guo, Meng Suo, Guowei Wang, Dong Chen, Lilin Su, Fuhuan Wang, Shipeng Ning, Kelong Fan, Xuan Wang   +10 more
wiley   +1 more source

Dual‐Gene Edited Extracellular Vesicles Remodel the Redox Homeostasis to Inhibit Ferroptosis in Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is driven by ferroptosis of nucleus pulposus cells (NPCs) as a core pathological mechanism. Nucleus pulposus progenitor cells (NPPCs), exhibiting stem cell‐like properties, yield extracellular vesicles (PEVs) with high affinity for NPCs and enable targeted phenotypic regulation.
Jing Yan, Yazhou Lin, Shuo Miao, Minghao Chao, Chengbai Dai, Ziwen Hao, Rui Chen, Ming Guan, Bin Pan, Fenglei Gao, Quan Zhou   +10 more
wiley   +1 more source

Nursing students' perceptions of the use of clinical simulation in biosafety education. [PDF]

Rev Esc Enferm USP
Canever BP, Oliveira SN, Peiter CC, Suplici SER, Gomes DC, Bellaguarda MLDR, Costa DGD, Magalhães ALP, Oliveira FM.   +8 more
europepmc   +1 more source

A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy

Advanced Science, EarlyView.
A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao, Yufei Lan, Min‐Goo Lee, Jinjun He, Yueran Pan, Eunji Kim, Xin Fu, Sungwook Jung, Wanxia Lu, Jinyue Fan, Haoxiang Chen, Yuanbo Zhao, Yuling Xu, Jong Seung Kim, Chao Zhang   +14 more
wiley   +1 more source

Artificial Intelligence‐Empowered Single‐Cell Phenotyping for Rapid, Automated Pathogen Diagnostics

Advanced Science, EarlyView.
This work presents an integrated diagnostic platform that combines microfluidic single‐cell bacterial detection with artificial intelligence‐driven analysis for rapid antimicrobial susceptibility testing. Single‐cell phenotyping enables assessment of antibiotic response in only a few cell replication cycles, while AI analysis supports precise bacterial
Sabita Khadka, Bushra Raahat, Spyros Tragoudas, Hui Li   +3 more
wiley   +1 more source

Assessment of water prophylaxis and biosafety in finfish aquaculture - current and emerging technologies. [PDF]

Front Microbiol
Bartkova S, Valentino F, Saraiva M, Duman M, Gerilovych A, Radosavljevic V, de Marco A, Saticioglu IB, Ay H.   +8 more
europepmc   +1 more source

Biosafety and biodiversity risks

What is Biosafety Risk? The potential biosafety risks of transgenic varieties have generated controversy in the international community. According to the U.S. National Research Council (2002), these risks include (1) the flow of transgenes, (2) evolution
Falck-Zepeda, José B., de Groote, Hugo, Smale, Melinda   +2 more
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