Results 181 to 190 of about 162,481 (277)
A biosafe mouse model for SARS-CoV-2 infection that more realistically simulates COVID-19 symptoms. [PDF]
Signal Transduct Target TherHuang X +9 more
europepmc +1 more source
Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation
Advanced Science, EarlyView.Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong +13 more
wiley +1 more source
Understanding biosafety practitioner perspectives. [PDF]
Politics Life SciGillum DR, Knight C, Vogel KM.
europepmc +1 more source
Innovative farming and forestry across the emerging world : the role of genetically modified crops and trees [PDF]
, 2016 De Buck, Sylvie +3 more
core
Coexistence in the EU-return of the moratorium on GM crops? [PDF]
, 2008 F Wu +14 more
core +2 more sources
Advanced Science, EarlyView.This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang +12 more
wiley +1 more source