Results 81 to 90 of about 162,481 (277)

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

open access: yesAdvanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu   +6 more
wiley   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni   +15 more
wiley   +1 more source

Biosafety challenges and the future landscape in Pakistan

open access: yesKhyber Medical University Journal
Sepsis is a major threat to global health, as highlighted by the Global Burden of Disease Study, which recorded an estimated 48.9 million cases of sepsis globally, resulting in 11.0 million sepsis-related deaths, accounting for 19.7% of all global deaths
Akhtar Sherin
doaj   +1 more source

Improvement of Tuberculosis Laboratory Capacity on Pemba Island, Zanzibar: A Health Cooperation Project. [PDF]

open access: yes, 2012
Low-income countries with high Tuberculosis burden have few reference laboratories able to perform TB culture. In 2006, the Zanzibar National TB Control Programme planned to decentralize TB diagnostics.
Emanuele Nicastri   +10 more
core   +2 more sources

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao   +8 more
wiley   +1 more source

Current status and future challenges of high-level biosafety laboratories in China

open access: yesJournal of Biosafety and Biosecurity, 2019
High-level biosafety laboratories are safe and secure platforms which integrate reliable containment, well-trained personnel, and specific biosafety manuals and practices to protect researchers from being infected while manipulating microbial pathogens ...
Yuan Zhiming
doaj   +1 more source

The strictest biosafety [PDF]

open access: yesProceedings of the National Academy of Sciences, 2014
In a small town in the middle of Montana, biologists handle deadly pathogens such as Ebola. Hamilton, with a population of about 4,500, hosts the National Institute of Allergy and Infectious Diseases’ Rocky Mountain Laboratories, one of a few dozen facilities worldwide equipped to deal with disease agents designated the strictest biosafety level 4 (BSL-
openaire   +2 more sources

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales   +12 more
wiley   +1 more source

Phage–Bacterial Interaction Alters Phenotypes Associated with Virulence in Acinetobacter baumannii

open access: yesViruses
Bacteriophages exert strong selection on their bacterial hosts to evolve resistance. At the same time, the fitness costs on bacteria following phage resistance may change their virulence, which may affect the therapeutic outcomes of phage therapy.
Greater Kayode Oyejobi   +6 more
doaj   +1 more source

Campus Update: April 1994 v. 6, no. 3 [PDF]

open access: yes, 1994
Monthly newsletter of the BU Medical ...
Boston University Medical Center
core   +1 more source

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