Results 31 to 40 of about 35,640 (270)

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

open access: yesAdvanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya   +14 more
wiley   +1 more source

Fostering the Biosecurity Norm: Biosecurity Education for the Next Generation of Life Scientists [PDF]

open access: yes, 2008
Sustainable education on biosecurity and dual use for life scientists is increasingly recognised as being an important element of broader efforts to achieve biosecurity.
Mancini, Guilio, Revill, James
core  

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

open access: yesAdvanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti   +3 more
wiley   +1 more source

Assessment of Knowledge, Attitude and Practice of Biosafety among University's Laboratory Staff

open access: yesHealth Dynamics
Background: Biosafety is crucial for protecting laboratory staff from infectious agents and hazardous biological materials. Inadequate knowledge of unsafe practices may increase the risk of laboratory-acquired infections and accidents.
Nik Nurfatin Athirah Nik Mohd Razali   +5 more
doaj   +1 more source

A One Health Evaluation of the Southern African Centre for Infectious Disease Surveillance [PDF]

open access: yes, 2018
Rooted in the recognition that emerging infectious diseases occur at the interface of human, animal, and ecosystem health, the Southern African Centre for Infectious Disease Surveillance (SACIDS) initiative aims to promote a trans-sectoral approach to ...
Anderson   +31 more
core   +4 more sources

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

open access: yesAdvanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee   +8 more
wiley   +1 more source

National Biodiversity Strategies and Action Plans: Natural Catalysts for Accelerating Action on Sustainable Development Goals [PDF]

open access: yes, 2016
In 2010, the Conference of Parties of the Convention on Biological Diversity (CBD) agreed to an ambitious set of 20 targets, called the Aichi Biodiversity Targets, as part of their commitment to the CBD Strategic Plan.
Jamison Ervin
core  

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Icarisid Ⅱ modulates mitochondrial dynamics for anti-HBV activity

open access: yesFrontiers in Pharmacology
IntroductionTo investigate the potential anti-hepatitis B virus (HBV) activity of Icariside Ⅱ (ICS Ⅱ), and elucidate its underlying mitochondrial dynamics mechanisms.MethodsThe study employed in vivo and in vitro assays to evaluate anti-HBV effects of ...
Zhengyun Liu   +8 more
doaj   +1 more source

Thermosensitive Hydrogel Wound Dressing Loaded with Bacteriophage Lysin LysP53

open access: yesViruses, 2022
Wound infections are prone to attacks from infectious pathogens, including multidrug resistant bacteria that render conventional antimicrobials ineffective.
Changchang Li   +6 more
doaj   +1 more source

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