Results 1 to 10 of about 105,153 (113)

Biosafety chemistry and biosafety materials: A new perspective to solve biosafety problems

Biosafety and Health, 2022
Coronavirus disease 2019 (COVID-19) has rapidly swept around the globe since its emergence near 2020. However, people have failed to fully understand its origin or mutation.
Haihua Xiao, Yingjie Yu, Jianxun Ding
exaly   +3 more sources

Integrating biosafety into medical microbiology education: student awareness, experiences, and teaching preferences [PDF]

BMC Medical Education
Background In the context of rapid scientific advancement and global health challenges, biosafety has become a critical concern for public health, scientific responsibility, and global security.
Lang Sun, Shuiping Liu
doaj   +2 more sources

Studies on developing a safe-management standard system for Chinese biosafety laboratories

Journal of Biosafety and Biosecurity, 2019
Standardization management is one of the key prerequisites to guarantee the effective and safe functioning of high-level biosafety laboratories. Since the outbreak of SARS, increasing numbers of biosafety laboratory levels have been established in China.
Feng W, Haixia Ma, Amei Deng, ZongSheng C, Zhiming Y   +4 more
exaly   +3 more sources

Biosafety management in high-biosafety-risk workshops for vaccine production in China

Journal of Biosafety and Biosecurity, 2023
This paper examines biosafety management in high-biosafety-risk workshops for vaccine production in China, focusing on the context of SARS-CoV-2 inactivated vaccine production.
Yu Zhang, Jia Lu, Fang Zhang, Jinming Li, Rongyu Shu, Changfu Guo, Xinfang Cao, Zejun Wang, Rui Jia   +8 more
doaj   +1 more source

Intranasal delivery of replicating mRNA encoding neutralizing antibody against SARS-CoV-2 infection in mice

Signal Transduction and Targeted Therapy, 2021
The lung is the prophylaxis target against SARS-CoV-2 infection, and neutralizing antibodies are a leading class of biological products against various infectious viral pathogen.
Jia-Qi Li, Zhe-Rui Zhang, Hong-Qing Zhang, Ya-Nan Zhang, Xiang-Yue Zeng, Qiu-Yan Zhang, Cheng-Lin Deng, Xiao-Dan Li, Bo Zhang, Han-Qing Ye   +9 more
doaj   +1 more source

Rational design of West Nile virus vaccine through large replacement of 3′ UTR with internal poly(A)

EMBO Molecular Medicine, 2021
The genus Flavivirus comprises numerous emerging and re‐emerging arboviruses causing human illness. Vaccines are the best approach to prevent flavivirus diseases.
Ya‐Nan Zhang, Na Li, Qiu‐Yan Zhang, Jing Liu, Shun‐Li Zhan, Lei Gao, Xiang‐Yue Zeng, Fang Yu, Hong‐Qing Zhang, Xiao‐Dan Li, Cheng‐Lin Deng, Pei‐Yong Shi, Zhi‐Ming Yuan, Shao‐Peng Yuan, Han‐Qing Ye, Bo Zhang   +15 more
doaj   +1 more source

Identification of potent human neutralizing antibodies against SARS-CoV-2 implications for development of therapeutics and prophylactics

Nature Communications, 2021
Applying neutralizing antibodies against SARS-CoV-2 to infected patients is a promising anti-viral treatment strategy. Here, Zhao et al. derive RBD-targeting monoclonal antibodies from a naïve human phage-displayed Fab library and show their ...
Shaojuan Zhao, Huajun Zhang, Xinglou Yang, Haiwei Zhang, Ying Chen, Yancheng Zhan, Xiaoqing Zhang, Rendi Jiang, Meiqin Liu, Lan Liu, Li Chen, Wei Tang, Cheng Peng, Xiaoxiao Gao, Zhe Zhang, Zhengli Shi, Rui Gong   +16 more
doaj   +1 more source

SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication

Cell Discovery, 2021
The newly emerging coronavirus SARS-CoV-2 causes severe lung disease and substantial mortality. How the virus evades host defense for efficient replication is not fully understood.
Zhou-Qin Zheng, Su-Yun Wang, Zhi-Sheng Xu, Yu-Zhi Fu, Yan-Yi Wang   +4 more
doaj   +1 more source

Biosafety and biosecurity capacity building: insights from implementation of the NUITM-KEMRI biosafety training model

Tropical Medicine and Health, 2018
The NUITM-KEMRI biosafety training program was developed for capacity building of new biosafety level three (BSL-3) laboratory users. The training program comprehensively covers biosafety and biosecurity theory and practice.
Betty Muriithi, Martin Bundi, Amina Galata, Gabriel Miringu, Ernest Wandera, Cyrus Kathiiko, Erick Odoyo, Martha Kamemba, Evans Amukoye, Sora Huqa, Mohammad Shah, Shingo Inoue, Yoshio Ichinose   +12 more
doaj   +1 more source

History of and suggestions for China’s biosafety legislation

Journal of Biosafety and Biosecurity, 2019
Biosafety has attracted an unprecedented amount of attention from the global community as an important element in national security. All biosafety issues are related to laws and therefore must be regulated accordingly. A preliminary biosafety legislation
Huigang Liang, Xiaowei Xiang, Haixia Ma, Zhiming Yuan   +3 more
doaj   +1 more source