Results 31 to 40 of about 20,909 (242)

CRISPR/Cas9-based knockout of BnaLYK compromises pattern-triggered immunity and resistance to Sclerotinia sclerotiorum in Brassica napus

BMC Plant Biology
Rapeseed (Brassica napus) is severely threatened by Sclerotinia sclerotiorum, the causal agent of Sclerotinia stem rot (SSR). The lack of fully resistant cultivars, combined with the genetic complexity of rapeseed as an allopolyploid species, has ...
Yingjun Liu, Xiaowen Yin, Pinyuan Jin, Huajian Zhang   +3 more
doaj   +1 more source

Icarisid Ⅱ modulates mitochondrial dynamics for anti-HBV activity

Frontiers in Pharmacology
IntroductionTo investigate the potential anti-hepatitis B virus (HBV) activity of Icariside Ⅱ (ICS Ⅱ), and elucidate its underlying mitochondrial dynamics mechanisms.MethodsThe study employed in vivo and in vitro assays to evaluate anti-HBV effects of ...
Zhengyun Liu, Haiyan Yang, Juan Wen, Dongyan Xiao, Dongyan Xiao, Wan Yu, Guo Luo, Qihai Gong, Huan Wang   +8 more
doaj   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Assessment of Knowledge, Attitude and Practice of Biosafety among University's Laboratory Staff

Health Dynamics
Background: Biosafety is crucial for protecting laboratory staff from infectious agents and hazardous biological materials. Inadequate knowledge of unsafe practices may increase the risk of laboratory-acquired infections and accidents.
Nik Nurfatin Athirah Nik Mohd Razali, Nurul Izzah Abdul Samad, Nursuhaili Mohd Amin, Mohd Firdaus Yhaya, Herdianti Hatta, Nurul Ainun Hamzah   +5 more
doaj   +1 more source

Thermosensitive Hydrogel Wound Dressing Loaded with Bacteriophage Lysin LysP53

Viruses, 2022
Wound infections are prone to attacks from infectious pathogens, including multidrug resistant bacteria that render conventional antimicrobials ineffective.
Changchang Li, Raphael Nyaruaba, Xiaowei Zhao, Heng Xue, Yuhong Li, Hang Yang, Hongping Wei   +6 more
doaj   +1 more source

Near‐Infrared Imaging of H2O2 in Plants With Nanosensors Under Environmentally Changing Conditions

Advanced Materials, EarlyView.
This paper reports a ratiometric nanosensor enabling robust, multivariate detection of stress signals (H2O2) in plants, with high resistance to light fluctuations and mechanical disturbances. Single‐walled carbon nanotubes serve as the sensor, Egyptian Blue nanosheets serve as a stable reference, and plant autofluorescence serves as a label‐free ...
Jiaqi Li, Bjoern F. Hill, Chen Ma, Juliana Gretz, Tanuja Kistwal, Janus A. C. Wartmann, Justus T. Metternich, Juan Pablo Giraldo, Sebastian Kruss   +8 more
wiley   +1 more source

Citrus Carotenoid Extracts Exert Anticancer Effects through Anti-Proliferation, Oxidative Stress, and Mitochondrial-Dependent Apoptosis in MCF-7 Cells

Foods, 2023
Citrus is a globally popular fruit crop that contains bioactive compounds with numerous health benefits. Carotenoids are one of the main bioactive compounds present in citrus pulp.
Juanjuan Wei, Yurong Li, Zimao Ye, Yi Li, Zhiqin Zhou   +4 more
doaj   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Identification and genomic insights into a plant probiotic Bacillus subtilis strain CF1 isolated from Protaetia brevitarsis frass

BMC Genomics
Background Plant probiotic bacteria offer a sustainable strategy for enhancing crop health and productivity. Insect frass has emerged as a unique niche for isolating beneficial microorganisms with novel traits.
Hongyu Wang, Xiaolong Hu, Junling Zhang, Yan Qin, Chenpu Wu, Shuan Zhao, Mian Hou, Beibei Cao, Jie Zhang, Changlong Shu, Kui Wang   +10 more
doaj   +1 more source

Immunoproteomic Screening of Candidate Antigens for the Preliminary Development of a Novel Multi-Component and Multi-Epitope Vaccine Against Streptococcus suis Infection

Vaccines
Background/Objectives: Streptococcus suis (SS), an important zoonotic pathogen, has caused significant economic losses to the global pig industry. Existing commercial vaccines for SS mainly provide effective protection against a single serotype.
Yue Zhang, Caiying Li, Yutong Feng, Qibing Gu, Jinwang Hu, Yuhang Li, Lu Xia, Shaopo Zu   +7 more
doaj   +1 more source