Mechanozyme: An Artificial Enzyme With a Mechanophore Framework
Advanced Science, EarlyView.Mechanical destabilization of a G‐quadruplex mechanophore in a DNAzyme markedly boosts its catalytic activity, demonstrating “mechanozymes” as artificial enzymes whose functions are modulated by mechanical stress exerted by ultrasonication. This mechanozyme principle is broadly applicable to control biomolecular activities.
Jiahao Ji +7 more
wiley +1 more source
Garland Rolling Circle Amplification Mediated Self-Priming Extension Strategy for Sensitive and Label-Free <i>Pseudomonas aeruginosa</i> Analysis in Perioperative Period. [PDF]
J Microbiol BiotechnolXu Y, Wei L.
europepmc +1 more source
Optimization of SWCNT‐FET Biosensors by Aptamer Engineering and Toehold‐Mediated Strand Displacement
Advanced Science, EarlyView.Aptamer‐based single‐walled carbon nanotube (SWCNT) field‐effect transistor (FET) biosensors are developed for label‐free, real‐time biomarker detection. Truncated DNA aptamers enhance sensitivity through improved conformational switching. A toehold‐mediated strand displacement (TMSD) strategy optimizes functionalization and simplifies fabrication. The
Haosen Miao +8 more
wiley +1 more source
High-Precision Detection of Magnetic Nanoparticles in Microfluidic Biosensing Systems. [PDF]
Biosensors (Basel)Brown D +5 more
europepmc +1 more source
Solid Ethanol as a Renewable, Low‐Toxicity, Electron‐Beam Direct Write, and Biomedical Material
Advanced Science, EarlyView.3D ice lithography (3DIL) enables the fabrication of intricate submicrometer objects using ethanol as a renewable starting material. This study combines process optimization, structural and material analysis, and biomedical applications, from cell culture scaffolds to the patterning of neurostimulation electrodes, demonstrating performance in both in ...
Bruno Perdigão +16 more
wiley +1 more source
Evaluation of optical biosensing techniques towards point-of-care diagnosis of active TB.
Doctoral Degree. University of KwaZulu-Natal Durban.Tuberculosis (TB) remains one of the leading causes of mortality and morbidity globally even though it is a treatable disease. South Africa is one of 22 countries with a high TB burden that accounts for
Maphanga, Charles Popo.
core
Electrochemical Stripping Analysis at Paper-Based (Bio)Sensors: Current State-of-the-Art and Prospects. [PDF]
Sensors (Basel)Kokkinos C, Economou A.
europepmc +1 more source
Advanced Science, EarlyView.A single‐molecule cascade supramolecular system comprising L/D‐FPy, CB[8], and SC4AD serves as an efficient light‐harvesting platform. It facilitates cascade energy transfer and chiral transfer to acceptor dyes. Co‐assembly with a PVA matrix produces a multicolor solid film that exhibits enhanced luminescence dissymmetry factors (glum), enabling ...
Yongxue Li +5 more
wiley +1 more source
Top 10 ground challenges in microsystems and nanoengineering. [PDF]
Microsyst NanoengMicrosystems & Nanoengineering.
europepmc +1 more source
Advanced Science, EarlyView.A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen +12 more
wiley +1 more source