Results 221 to 230 of about 5,506,086 (276)

Organic electrochemical transistors for neural recording and modulation: From mixed‐conduction physics to closed‐loop biointerfaces

InfoMat, EarlyView.
OECT‐based neural interfaces integrate mixed ionic‐electronic transduction, soft biointegration, multimodal sensing, and closed‐loop modulation, enabling adaptive recording, neurochemical monitoring, and intelligent therapeutic strategies. Abstract Next‐generation neural interfaces increasingly aim to couple neural recording with local processing and ...
Chao Zhao, Zhongqing Sun, Shijie Wang, Bingjun Wang, Zixuan Yuan, Yaomin Guo, Jie Zhao, Leyuan Li, Xiaomu Wang, Wen Jiang, Wei Ma   +10 more
wiley   +1 more source

Scalable optical metasurfaces for ultrasensitive, label-free and real-time biosensing. [PDF]

Med X
Wang H, Deng N, Xiao Y, Pandey A, Wang S, Cai H.   +5 more
europepmc   +1 more source

Advancing biosensing techniques for detection of antimicrobial resistance genes and antibiotics in water

Antimicrobial resistance (AMR) poses a significant global public health threat requiring urgent attention for surveillance of antibiotic resistance genes (ARGs) and antibiotics in the environment. In this PhD study, a real-time fluorescent detection assay of antimicrobial resistance genes (ARGs) was developed to specifically target two key ARGs, tet(M)
openaire   +1 more source

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

Interdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao, Panpan Qiao, Yujing Zeng, Murtaza Sayed, Qin Mi, Juan Zhang, Genxi Li   +6 more
wiley   +1 more source

Research Advances in Diagnostic Methods for Prevalent Neurological Diseases. [PDF]

Biosensors (Basel)
Lv M, Sun X, Wang X.
europepmc   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Combining Asymmetric PCR with PAM-Independent Cas12a Analysis of Single-Stranded Amplicons for On-Site Nucleic Acid Testing. [PDF]

Biosensors (Basel)
Ptitsyn KG, Timoshenko OS, Khmeleva SA, Kurbatov LK, Stepanova AA, Nikiforova EM, Suprun EV, Radko SP, Lisitsa AV.   +8 more
europepmc   +1 more source

Controlling Growth of Ultrasmall Sub‐10 nm Silver Nanoparticles From Cotinus coggygria Scop. Extract and Evaluation of Its In Vitro Anti‐Breast Cancer, Antioxidant and Antimicrobial Activity

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study highlights the potential use of Cotinus coggygria Scop. plant extract in a single‐step synthesis of biocompatible and ultrasmall AgNPs for in vitro applications. Herein, microscopic analyses revealed that AgNP exposure did not induce appreciable morphological changes in CRL‐4010 cells, whereas MCF‐7 and MDA‐MB‐231 cells exhibited ...
Ümran Ünüvar, Tuğba Nur Aslan, Suray Pehlivanoğlu, Kübra Ece Coşkuner   +3 more
wiley   +1 more source

Emerging Argonaute-based food safety detection: from amplification to amplification-free manner. [PDF]

Front Microbiol
Kang W, Li Y, Zhao L, Ma L, Bai Y, Feng F.   +5 more
europepmc   +1 more source