Near-infrared light-controlled catalytic hairpin assembly fluorescent biosensor for the sensitive and specific detection of fibroblast activation protein. [PDF]
Wu J, Zheng X, Huang J, Chen E.
europepmc +1 more source
An immunomagnetic‐MXene bifunctional probe integrated with THz metamaterials enables ultrasensitive and specific detection of pancreatic cancer‐derived exosomes. Dual biomarker recognition ensures high specificity, while MXene signal amplification achieves a detection limit of 647 particles mL−1.
Weidong Jin +8 more
wiley +1 more source
Lab-on-a-chip device with an integrated surface acoustic wave micromixer for enhanced porous silicon biosensor performance. [PDF]
Nyenhuis J +8 more
europepmc +1 more source
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo +5 more
wiley +1 more source
A Wearable Respiratory Monitor for Home-Based Screening and Stratification of Obstructive Sleep Apnea: A Pilot Study in Participants with Intermediate-to-High STOP-Bang Scores. [PDF]
Kolukisa Birgec B, Toprak B, Mullen AB.
europepmc +1 more source
Re‐Thinking Electronic Circuit Design Through Emerging Reconfigurable Field Effect Transistors
Graphical illustration of reconfigurable field effect transistor (RFET) operation modes, including n‐type, p‐type, and ambipolar transport, as well as their areas of application discussed in this review: digital circuit design, analog circuit design, post‐Shannon computing, and sensing. ABSTRACT Reconfigurable field‐effect transistors, short RFETs, are
Jens Trommer +19 more
wiley +1 more source
Hybrid machine learning driven optimization of multilayer SPR sensor for high sensitivity milk fat detection. [PDF]
Utshob MAAI +4 more
europepmc +1 more source
An Integrated Artificial Intelligence Framework for Nanomedicine Engineering
This review outlines a closed‐loop AI ecosystem for nanomedicine engineering. By synergizing multimodal data harmonization, objective‐driven AI architectures, and automated high‐throughput validation, this “Design‐Make‐Test‐Analyze” (DMTA) workflow transforms traditional heuristic formulation into a predictive, self‐optimizing paradigm, accelerating ...
Meichen Dong +10 more
wiley +1 more source
A modular APEX biosensor enables sensitive and visualized monitoring of viral protease activity. [PDF]
Li B +13 more
europepmc +1 more source
Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer [PDF]
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Alexandrou S +17 more
europepmc +2 more sources

