Results 51 to 60 of about 134,083 (309)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Novel approaches to engineer glucose biosensors [PDF]

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Designing a biosensor capable of continuously monitoring blood glucose concentration in people with diabetes has been a major challenge for over three ...
Trzebinski, Jakub
core  

Review of Electrochemical DNA Biosensors for Detecting Food Borne Pathogens [PDF]

open access: yes, 2019
The vital importance of rapid and accurate detection of food borne pathogens has driven the development of biosensor to prevent food borne illness outbreaks.
Wei Zhang   +4 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Photonic Crystal-Based Sensing and Imaging of Potassium Ions

open access: yesChemosensors, 2014
We report on a method for selective optical sensing and imaging of potassium ions using a sandwich assembly composed of layers of photonic crystals and an ion-selective membrane.
Christoph Fenzl   +3 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Carrier systems and biosensors for biomedical applications. [PDF]

open access: yes, 2007
This chapter addresses both carrier systems and biosensors which are often applied directly to tissues, either as skin patches, implanted or ingested by a variety of routes.
Higson, Seamus P. J., Davis, Frank
core  

Biosensors for the Detection of Bacterial and Viral Clinical Pathogens [PDF]

open access: yes, 2020
Biosensors are measurement devices that can sense several biomolecules, and are widely used for the detection of relevant clinical pathogens such as bacteria and viruses, showing outstanding results.
Mary Lopretti-Correa   +5 more
core   +1 more source

Label-Free Bound-States-in-the-Continuum Biosensors [PDF]

open access: yes, 2022
Bound states in the continuum (BICs) have attracted considerable attentions for biological and chemical sensing due to their infinite quality (Q)-factors in theory.
Yi Zhou   +17 more
core   +1 more source

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