Results 41 to 50 of about 335,990 (253)

A Cox Model for Biostatistics of the Future

open access: yes, 2004
Professor Sir David R. Cox (DRC) is widely acknowledged as among the most important scientists of the second half of the twentieth century. He inherited the mantle of statistical science from Pearson and Fisher, advanced their ideas, and translated ...
Zeger, Scott L.   +2 more
core  

Measurements of Accuracy in Biostatistics

open access: yes, 2018
Due to the nature of biological and medical data, biostatistics has been playing an increasing role in a wide range of applications in biology and medicine.
Wang, Haiying / HY   +5 more
core   +1 more source

Biostatistics for gastroenterologists. Part I.

open access: yes, 2023
20.500.12530/87854Statistical tests are the foundation on which data analysis for all types of clinical, basic and epidemiological research relies upon. Clinicians need to understand these tests and the basics of biostatistics to correctly relay the data
Stallings, Elena
core   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

open access: yesAdvanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang   +12 more
wiley   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

open access: yesAdvanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu   +5 more
wiley   +1 more source

Essentials of Biostatistics & Research Methodology

open access: yes, 2020
The 3rd edition of “Essentials of Biostatistics & Research Methodology” by Dr. Indranil Saha & Dr. Bobby Paul is one of the complete books on Biostatistics & Research Methodology for Undergraduates, Postgraduates & Ph.D.
Bahurupi, Yogesh   +1 more
core   +1 more source

ZDHHC17‐Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance

open access: yesAdvanced Science, EarlyView.
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang   +7 more
wiley   +1 more source

CrossMatAgent: AI‐Assisted Design of Manufacturable Metamaterial Patterns via Multi‐Agent Generative Framework

open access: yesAdvanced Intelligent Discovery, EarlyView.
CrossMatAgent is a multi‐agent framework that combines large language models and diffusion‐based generative AI to automate metamaterial design. By coordinating task‐specific agents—such as describer, architect, and builder—it transforms user‐provided image prompts into high‐fidelity, printable lattice patterns.
Jie Tian   +12 more
wiley   +1 more source

Principles of Biostatistics

open access: yes, 1993
524 Halaman.; 24 ...
Erina Hidayati   +2 more
core  

Covariate Assisted Principal Regression for Covariance Matrix Outcomes

open access: yes, 2019
In this study, we consider the problem of regressing covariance matrices on associated covariates. Our goal is to use covariates to explain variation in covariance matrices across units. As such, we introduce Covariate Assisted Principal (CAP) regression,
Zhao, Yi   +4 more
core   +1 more source

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