Results 61 to 70 of about 420,917 (289)

Basic concepts in research methodology and biostatistics for head and neck oncologists

Journal of Head & Neck Physicians and Surgeons, 2019
Research is an integral part of head and oncology. Understanding the methodology of research, either clinical or basic science, is important for an oncologist involved in such projects.
Krishnakumar Thankappan
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Reference Intervals (RIs) of the Bone Turnover Markers (BTMs) in Children and Adolescents: A Proposal for Effective Use

Biomedicines
Background/Objectives: Bone turnover markers (BTMs) can provide information on the bone growth of apparently healthy children and adolescents or useful results in the diagnosis and monitoring of the disease condition, comparing them with appropriate ...
Vincenzo Brescia, Roberto Lovero, Antonietta Fontana, Roberta Zerlotin, Silvia Concetta Colucci, Maria Grano, Angela Pia Cazzolla, Francesca Di Serio, Vito Crincoli, Maria Felicia Faienza   +9 more
doaj   +1 more source

Differences Due to Sex and Sweetener on the Bioavailability of (Poly)phenols in Urine Samples: A Machine Learning Approach

Metabolites, 2023
Metabolic diseases have been related to the overdrinking of high-sugar content beverages. As a result, the demand for alternative formulations based on plant-based ingredients with health-promoting properties has increased during the last few years ...
Diego Hernández-Prieto, Alberto Garre, Vicente Agulló, Cristina García-Viguera, Jose A. Egea   +4 more
doaj   +1 more source

Biostatistics in Medical Laboratory Science: Implications

, 2022
It is well acknowledged that biostatistics is a crucial tool in medical, clinical, and health research. The application of statistics to biological fields, medical fields, or medical studies is known as biostatistics.
Johnkennedy Nnodim, Amaewhule, Chynwe Tim, Eghujovwo, Pamela Enohor   +2 more
core   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Essentials of Biostatistics & Research Methodology [PDF]

, 2020
The 3rd edition of “Essentials of Biostatistics & Research Methodology” by Dr. Indranil Saha & Dr. Bobby Paul is one of the complete books on Biostatistics & Research Methodology for Undergraduates, Postgraduates & Ph.D.
Bahurupi, Yogesh, Sai, Bheemisetti Manideep   +1 more
core   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Standard statistical methods and calculation of sample size in Medical education research [PDF]

Perspectives In Medical Research, 2018
After confirmation of any line and area of Research work, the Basic Question starts with Collection of Sample size determination, but before that in a health science research "why statistical methods are so important?" Simple answer is that ...
Dr . Gopinath Agnihotram
doaj  

Best Practices for Biostatistical Consultation and Collaboration in Academic Health Centers [PDF]

, 2016
Given the increasing level and scope of biostatistics expertise needed at academic health centers today, we developed best practices guidelines for biostatistics units to be more effective in providing biostatistical support to their institutions, and in
Rocke, David M., Lindsell, Christopher J, Rocke, David M, Lindsell, Christopher J., Rudser, Kyle D, Kim, Mimi, Oster, Robert A, Davey, Cynthia S, Perkins, Susan M, Epidemiology, and Research Design Key Function Committee of the Clinical and Translational Science Consortium the Biostatistics, Mazumdar, Madhu, Peduzzi, Peter N, Bacchetti, Peter, Rudser, Kyle D., Oster, Robert A., Davey, Cynthia S., Perkins, Susan M.   +16 more
core   +1 more source