Results 191 to 200 of about 1,499,955 (388)
Advanced Science, EarlyView.This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao +17 more
wiley +1 more source
The Utilization of Squalene in the Biosynthesis of Cholesterol
, 1953 Robert Langdon, Konrad Bloch
openalex +1 more source
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
Cell, 2015 J. Yano +9 more
semanticscholar +1 more source
D‐glucuronyl C5‐Epimerase Binds to EGFR to Suppress Kidney Fibrosis
Advanced Science, EarlyView.Glucuronyl C5‐epimerase (Hsepi, gene name Glce) is a key enzyme catalyzing heparan sulfate (HS) chain biosynthesis in HS proteoglycans, which are ubiquitously expressed on cell membranes. In normal renal tubular cells, Glce binds to the intracellular domains of EGFR, maintaining stable and orderly EGFR phosphorylation.
Xiaoqi Jing +9 more
wiley +1 more source
Transcriptome‐Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean
Advanced Science, EarlyView.This study employs transcriptome‐wide association studies (TWAS) to identify 201 long non‐coding RNAs (lncRNAs) associated with seed weight. Expression quantitative trait locus (eQTL) analysis reveals dynamic and static regulatory variants controlling lncRNA expression across development.
Xiang Wang +8 more
wiley +1 more source
Advanced Science, EarlyView.In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang +11 more
wiley +1 more source
BIOSYNTHESIS OF ADRENALINE AND NORADRENALINE IN VITRO
, 1957 McC. Goodall, Norman Kirshner
openalex +1 more source