Results 211 to 220 of about 1,266,322 (341)

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

Advanced Science, EarlyView.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang, Chong Yang, Dayuan Luo, Pingting Liu, Zhen Zeng, Weilin Peng, Dongzi Peng, Hao Su, Xiaoxiong Xiao, Haiqin Wang, Xin Jin   +10 more
wiley   +1 more source

VrNAC25 Promotes Anthocyanin Synthesis in Mung Bean Sprouts Synergistically with VrMYB90. [PDF]

Plants (Basel)
Zhu Y, Liu Y, You F, Wan Z, Guo M, Lu M, Yang L, Wang X, Yang J, Jia L, Su N.   +10 more
europepmc   +1 more source

The biosynthesis of tetracycline [PDF]

Pure and Applied Chemistry, 1973
Z, Vanĕk, Z, Hostálek, M, Blumauerová, K, Mikulík, M, Podojil, V, Bĕhal, V, Jechová   +6 more
openaire   +2 more sources

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, EarlyView.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

Biosynthesis Regulation of Secondary Metabolite Production in <i>Fusarium</i> Fungi. [PDF]

J Fungi (Basel)
Amuzu P, Pan X, Hou X, Li Y, Sun J, Huang Y, Wang P, Liu L, Lai D, Zhou L.   +9 more
europepmc   +1 more source

Fatty Acid Biosynthesis Inhibition Increases Reduction Potential in Neuronal Cells under Hypoxia [PDF]

, 2016
Stephen A. Brose, Svetlana A. Golovko, Mikhail Y. Golovko   +2 more
openalex   +1 more source

CRISPR/Cas9-mediated gene editing of vacuolar ATPase subunit d mediates phytohormone biosynthesis and virus resistance in rice

, 2023
Qinghua Lu, Xiangwen Luo, Xiao Yang, Tong Zhou, Yu Zhang, Ying Lan, Deyong Zhang, Limin Zheng, Yixin Li, Li Li, Songbai Zhang, Yong Liu   +11 more
openalex   +1 more source

Replacing BPA: Structural Substitutes BPAF Binding to the Progesterone Receptor Elevates Breast Cancer Risk

Advanced Science, EarlyView.
This study demonstrates that bisphenol analogues, particularly BPAF, bind to progesterone receptor, promoting breast cancer cell proliferation, migration, and mammary tumor growth, indicating that bisphenol A substitutes may pose equal or greater health risks.
Xiaotong Ji, Peilin Li, Haoyang Wu, Linzhuo Shen, Xiaoyun Wu, Peiyun Jiang, Yating Li, Xiaozheng Zhang, Huifeng Yue   +8 more
wiley   +1 more source

MeJA Elicitation on Flavonoid Biosynthesis and Gene Expression in the Hairy Roots of <i>Glycyrrhiza glabra</i> L. [PDF]

Genes (Basel)
Zhu Y, Wang B, Xue B, Wang R, Tang G, Zhu T, Zhao M, Li T, Liao C, Zhang H, Liu D, Chen J, Wang L.   +12 more
europepmc   +1 more source

Two plastidial lysophosphatidic acid acyltransferases differentially mediate the biosynthesis of membrane lipids and triacylglycerols in Phaeodactylum tricornutum

, 2023
Lingjie You, Ada Połońska, Katarzyna Jasieniecka‐Gazarkiewicz, Fabien Richard, Juliette Jouhet, Éric Maréchal, Antoni Banaś, Hanhua Hu, Yufang Pan, Xiahui Hao, Hu Jin, Andrew E. Allen, Alberto Amato, Yangmin Gong   +13 more
openalex   +2 more sources