Results 241 to 250 of about 1,068,298 (347)

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.

Molecules and Cells, 2000
B. Goodwin, Stacey A. Jones, R. R. Price, M. Watson, D. D. Mckee, L. Moore, C. Galardi, Joan G. Wilson, M. Lewis, M. Roth, P. Maloney, T. Willson, S. Kliewer   +12 more
semanticscholar   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

A beneficial bacterium mitigates drought stress by upregulating the flavonoid biosynthetic pathway in <i>Arabidopsis</i>. [PDF]

Plant Signal Behav
Kimotho RN, Gachomo EW.
europepmc   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Enhanced spinosad production in <i>Saccharopolyspora spinosa</i> by employing mannose as an extracellular carbon reservoir and optimizing acetyl-CoA supply pathway. [PDF]

Synth Syst Biotechnol
Zhu Z, Zhao Q, Zhu Y, Shuai L, Li J, Liu Q, Liu X, Wang S, Jin D, Dai Z, Xia L, Liu H, Rang J.   +12 more
europepmc   +1 more source

Three types of enzymes complete the furanocoumarins core skeleton biosynthesis in Angelica sinensis

Kaixuan Wang, Huihui Zeng, Yiqun Dai, Zixuan Wang, Huanying Tang, Junde Li, Xingchen Lu, Neng Jiang, Guoyong Xie, Yan Zhu, Yucheng Zhao, Minjian Qin   +11 more
openalex   +1 more source

The roles of AVR4 in fungal virulence,cercosporin biosynthesis and its potential use in host induced gene silencing for controlling cercospora leaf blight disease of soybeans

, 2017
Josielle Santos Rezende, Josielle Santos Rezende   +1 more
openalex   +2 more sources

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

Advanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li, Bao Dong, Zheng‐Lin Ren, Xue‐Guang Zhu, Quan Lei, Yoonseong Park, Jin‐Jun Wang, Hong‐Bo Jiang   +7 more
wiley   +1 more source