Results 261 to 270 of about 794,439 (319)

Parallel Pathways and Alternative Macrocyclizations in the Biosynthesis of Largimycins by Cytochrome P450 Minus Mutants of <i>Streptomyces argillaceus</i>. [PDF]

J Nat Prod
Becerril A, Pérez-Victoria I, Martín J, Salas JA, Reyes F, Méndez C.   +5 more
europepmc   +1 more source

SERRATE Regulates Floral Meristem Activity by Antagonizing SHOOT MERISTEMLESS and Repressing Cytokinin Signaling

Advanced Science, EarlyView.
Floral meristem (FM) activity is crucial for the initiation of floral organs. In this study, SE represses IPT7 expression and cytokinin signaling via both the miR171c‐5p–KNAT2 and miR164c–CUC1/2–KNAT2 regulatory modules, thereby repressing FM activity. In contrast, STM induces both KNAT2 and IPT7 expression.
Wen Yang, Yiting Wang, Yuxin You, Zhiyue Wu, Dongbao Li, Xin Wang, Yongsheng Chang, Hang Zhao, Tao Zhu, Dijun Chen, Wei Chen, Bo Sun   +11 more
wiley   +1 more source

Heterojunction‐Engineered Mass Spectrometry Platform for Deciphering Serum Metabolic Fingerprints in Diagnosis of Respiratory Diseases

Advanced Science, EarlyView.
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen, Chaoqi Wang, Xi Yu, Yuming Jiang, Yijiao Qu, Huihui Fu, Yuyin Bu, Xiaoyong Zhang, Zongxiu Nie   +8 more
wiley   +1 more source

Integrative Transcriptomic and Metabolomic Analyses Provide Insights into the Regulatory Basis of <i>Streptomyces pactum</i> Act12-Associated Root Development in Wheat. [PDF]

Plants (Basel)
Zhang J, Wen H, Wang Y, Wang Z, Zheng X, Shan H, Yang B.   +6 more
europepmc   +1 more source

STAID: A Self‐Refining Deep Learning Framework for Spatial Cell‐Type Deconvolution with Biologically Informed Modeling

Advanced Science, EarlyView.
STAID is a unified deep learning framework that couples iterative pseudo‐spot refinement with neural network training through a feedback loop and exploits gene co‐expression information to model higher‐order interactions, achieving accurate and robust cell‐type deconvolution in spatial transcriptomics.
Jixin Liu, Shuli Sun, Zhengliang Lv, Xinyu Liu, Yihua Wang, Bingqiang Liu   +5 more
wiley   +1 more source

Advances of Microneedle Patch in Diabetic Wound Healing

Pharmaceutical Fronts
Yong-Nian Zeng, Yin-Li Jin, Wei Li
doaj   +1 more source

A Systematic Review of Folate and the Human Enteric Microbiome: Biological Mechanisms and Clinical Implications. [PDF]

Int J Mol Sci
Khanduja R, Frye RE.
europepmc   +1 more source

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

Advanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang, Meng‐Hao Li, Liang Cheng, Tian‐Shou Zhang, Hui Hui, Yan Wang, Hong‐Pu Zhang, Bo‐Wen Liu, Lin Wang, Ying‐Wei Yang   +9 more
wiley   +1 more source

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Biosynthesis of cyclitols

Natural Product Reports, 2022
Carbocycle formation in the biosynthesis of the majority of cyclitols derived from carbohydrate origin are catalyzed by myo-inositol phosphate synthase (MIPS) family, dehydroquinate synthase (DHQS) family, radical SAM enzymes, and ribosyltransferase-isomerase type enzymes.
Fumitaka Kudo, Tadashi Eguchi
openaire   +2 more sources