Results 1 to 10 of about 330,730 (300)

Analytics for metabolic engineering [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2015
Realizing the promise of metabolic engineering has been slowed by challenges related to moving beyond proof-of-concept examples to robust and economically viable systems. Key to advancing metabolic engineering beyond trial-and-error research is access to
Christopher J Petzold   +4 more
doaj   +3 more sources

Genetic-Metabolic Coupling for Targeted Metabolic Engineering [PDF]

open access: yesCell Reports, 2017
Summary: Production of chemicals in microbes often employs potent biosynthetic enzymes, which can interact with the microbial native metabolism to affect cell fitness and product yield.
Stefano Cardinale   +2 more
doaj   +3 more sources

Metabolic pathway engineering

open access: yesSynthetic and Systems Biotechnology, 2018
Hal S. Alper
doaj   +3 more sources

Type I-F CRISPR-PAIR platform for multi-mode regulation to boost extracellular electron transfer in Shewanella oneidensis

open access: yesiScience, 2022
Summary: Bio-electrochemical systems are based on extracellular electron transfer (EET), whose efficiency relates to the expression level of numerous genes.
Yaru Chen   +3 more
doaj   +1 more source

Engineering Cellular Metabolism [PDF]

open access: yesCell, 2016
Metabolic engineering is the science of rewiring the metabolism of cells to enhance production of native metabolites or to endow cells with the ability to produce new products. The potential applications of such efforts are wide ranging, including the generation of fuels, chemicals, foods, feeds, and pharmaceuticals.
Nielsen, Jens, Keasling, Jay D
openaire   +6 more sources

The virus as metabolic engineer [PDF]

open access: yesBiotechnology Journal, 2010
AbstractRecent genome‐wide screens of host genetic requirements for viral infection have reemphasized the critical role of host metabolism in enabling the production of viral particles. In this review, we highlight the metabolic aspects of viral infection found in these studies, and focus on the opportunities these requirements present for metabolic ...
Nathaniel D, Maynard   +3 more
openaire   +2 more sources

A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2

open access: yesiScience, 2020
Summary: The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through technologies such as ...
Rajesh Reddy Bommareddy   +6 more
doaj   +1 more source

METABOLIC ENGINEERING OF SOLVENTOGENIC Clostridia [PDF]

open access: yesBiotechnologia Acta, 2019
Literary data on the organization of the genome, the connection of genes with the production and regulation of solvents, and the metabolic engineering of solventogenic clostridia are presented.
O. Tigunova   +3 more
doaj   +1 more source

Metabolic Engineering of Bacteria [PDF]

open access: yesIndian Journal of Microbiology, 2011
Yield and productivity are critical for the economics and viability of a bioprocess. In metabolic engineering the main objective is the increase of a target metabolite production through genetic engineering. Metabolic engineering is the practice of optimizing genetic and regulatory processes within cells to increase the production of a certain ...
Ravi R, Kumar, Satish, Prasad
openaire   +2 more sources

Considering Strain Variation and Non-Type Strains for Yeast Metabolic Engineering Applications

open access: yesLife, 2022
A variety of yeast species have been considered ideal hosts for metabolic engineering to produce value-added chemicals, including the model organism Saccharomyces cerevisiae, as well as non-conventional yeasts including Yarrowia lipolytica, Kluyveromyces
Xiunan Yi, Hal S. Alper
doaj   +1 more source

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