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The automated Galaxy-SynBioCAD pipeline for synthetic biology design and engineering
Automated design and build processes can rapidly accelerate work in synthetic biology and metabolic engineering. Here the authors present Galaxy-SynBioCAD, a toolshed for synthetic biology, metabolic engineering, and industrial biotechnology that they ...
Joan Hérisson +13 more
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Mini-review: In vitro Metabolic Engineering for Biomanufacturing of High-value Products
With the breakthroughs in biomolecular engineering and synthetic biology, many valuable biologically active compound and commodity chemicals have been successfully manufactured using cell-based approaches in the past decade.
Weihua Guo, Jiayuan Sheng, Xueyang Feng
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The application of microfluidic-based technologies in the cycle of metabolic engineering
The process of metabolic engineering consists of multiple cycles of design, build, test and learn, which is typically laborious and time-consuming. To increase the efficiency and the rate of success of strain engineering, novel instrumentation must be ...
Xiaoyan Ma, Yi-Xin Huo
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Metabolic regulation of gene expression for the microbial production of fine chemicals, such as organic acids, is an important research topic in post-genomic metabolic engineering.
Jia-Wei Li +3 more
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Key applications of plant metabolic engineering.
Great strides have been made in plant metabolic engineering over the last two decades, with notable success stories including Golden rice. Here, we discuss the field's progress in addressing four long-standing challenges: creating plants that satisfy ...
Warren Lau +3 more
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The path to next generation biofuels: successes and challenges in the era of synthetic biology
Volatility of oil prices along with major concerns about climate change, oil supply security and depleting reserves have sparked renewed interest in the production of fuels from renewable resources.
Gonzalez Ramon +2 more
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Systems biology aims at achieving a system-level understanding of living organisms and applying this knowledge to various fields such as synthetic biology, metabolic engineering, and medicine. System-level understanding of living organisms can be derived
Bor-Sen Chen, Chia-Chou Wu
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Microbial metabolic engineering
Lawrence P. Wackett
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Metabolic Engineering of Oleaginous Yeasts for Production of Fuels and Chemicals
Oleaginous yeasts have been increasingly explored for production of chemicals and fuels via metabolic engineering. Particularly, there is a growing interest in using oleaginous yeasts for the synthesis of lipid-related products due to their high ...
Shuobo Shi +4 more
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Synthetic metabolic engineering of functional crops: Boosting nutrition and human health
A growing global population and the increasing prevalence of diet-related health issues such as “hidden hunger”, obesity, hypertension, and diabetes necessitate a fundamental rethinking of crop design and breeding.
Nan Chai +14 more
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