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METABOLIC ENGINEERING OF SOLVENTOGENIC Clostridia [PDF]

open access: yesBiotechnologia Acta, 2019
Literary data on the organization of the genome, the connection of genes with the production and regulation of solvents, and the metabolic engineering of solventogenic clostridia are presented.
O. Tigunova   +3 more
doaj   +1 more source

Genomic and proteomic biases inform metabolic engineering strategies for anaerobic fungi. [PDF]

open access: yes, 2020
Anaerobic fungi (Neocallimastigomycota) are emerging non-model hosts for biotechnology due to their wealth of biomass-degrading enzymes, yet tools to engineer these fungi have not yet been established.
Albà   +92 more
core   +1 more source

Considering Strain Variation and Non-Type Strains for Yeast Metabolic Engineering Applications

open access: yesLife, 2022
A variety of yeast species have been considered ideal hosts for metabolic engineering to produce value-added chemicals, including the model organism Saccharomyces cerevisiae, as well as non-conventional yeasts including Yarrowia lipolytica, Kluyveromyces
Xiunan Yi, Hal S. Alper
doaj   +1 more source

Microbial cell factories based on filamentous bacteria, yeasts, and fungi

open access: yesMicrobial Cell Factories, 2023
Background Advanced DNA synthesis, biosensor assembly, and genetic circuit development in synthetic biology and metabolic engineering have reinforced the application of filamentous bacteria, yeasts, and fungi as promising chassis cells for chemical ...
Qiang Ding, Chao Ye
doaj   +1 more source

Metabolic engineering of micronutrients in crop plants [PDF]

open access: yes, 2016
Micronutrient deficiency is a widespread phenomenon, most prevalent in developing countries. Being causally linked to the occurrence of a range of diseases, it affects billions of people worldwide. Enhancing the content of micronutrients in crop products
Blancquaert, Dieter   +3 more
core   +2 more sources

The logics of metabolic regulation in bacteria challenges biosensor-based metabolic engineering

open access: yesMicrobial Cell, 2017
Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of many new applications for health ...
Matthieu Jules
doaj   +1 more source

Advances in the optimization of central carbon metabolism in metabolic engineering

open access: yesMicrobial Cell Factories, 2023
Central carbon metabolism (CCM), including glycolysis, tricarboxylic acid cycle and the pentose phosphate pathway, is the most fundamental metabolic process in the activities of living organisms that maintains normal cellular growth.
Zhenke Wu   +7 more
doaj   +1 more source

Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha

open access: yesSynthetic and Systems Biotechnology, 2022
Bio-manufacturing via microbial cell factory requires large promoter library for fine-tuned metabolic engineering. Ogataea polymorpha, one of the methylotrophic yeasts, possesses advantages in broad substrate spectrum, thermal-tolerance, and capacity to ...
Chunxiao Yan   +6 more
doaj   +1 more source

Plant Metabolic Engineering [PDF]

open access: yesPlant Physiology, 2001
Metabolic engineering is generally defined as the redirection of one or more enzymatic reactions to produce new compounds in an organism, improve the production of existing compounds, or mediate the degradation of compounds.
openaire   +2 more sources

The LASER database: Formalizing design rules for metabolic engineering

open access: yesMetabolic Engineering Communications, 2015
The ability of metabolic engineers to conceptualize, implement, and evaluate strain designs has dramatically increased in the last decade. Unlike other engineering fields, no centralized, open-access, and easily searched repository exists for cataloging ...
James D. Winkler   +2 more
doaj   +1 more source

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