Results 11 to 20 of about 9,631,074 (339)
Advances in the optimization of central carbon metabolism in metabolic engineering
Microbial Cell Factories, 2023 Central carbon metabolism (CCM), including glycolysis, tricarboxylic acid cycle and the pentose phosphate pathway, is the most fundamental metabolic process in the activities of living organisms that maintains normal cellular growth.
Zhenke Wu +7 more
doaj +2 more sources
Analytics for metabolic engineering [PDF]
Frontiers in Bioengineering and Biotechnology, 2015 Realizing the promise of metabolic engineering has been slowed by challenges related to moving beyond proof-of-concept examples to robust and economically viable systems. Key to advancing metabolic engineering beyond trial-and-error research is access to
Christopher J Petzold +4 more
doaj +3 more sources
Genetic-Metabolic Coupling for Targeted Metabolic Engineering [PDF]
Cell Reports, 2017 Summary: Production of chemicals in microbes often employs potent biosynthetic enzymes, which can interact with the microbial native metabolism to affect cell fitness and product yield.
Stefano Cardinale +2 more
doaj +3 more sources
The logics of metabolic regulation in bacteria challenges biosensor-based metabolic engineering
Microbial Cell, 2017 Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of many new applications for health ...
Matthieu Jules
doaj +2 more sources
Auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast
Nature Communications, 2021 Loss-of-function experiments are used in metabolic engineering to understand and optimise metabolism. Here, the authors apply auxin inducible protein degradation to test different metabolic engineering strategies for improved terpenoid production in ...
Zeyu Lu +4 more
doaj +2 more sources
Metabolic Engineering for Gibberellic Acid Production in Fusarium fujikuroi: Advances and Perspectives [PDF]
MoleculesGibberellic acids (GAs) are a class of tetracyclic diterpene carboxylic acid compounds produced by green plants, fungi, and bacteria, which have a wide range of applications in agricultural production and food ingredients processing.
Lianghong Yin +9 more
doaj +2 more sources
Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene. [PDF]
Metabolic Engineering, 2019 Saccharomyces cerevisiae is an efficient host for natural-compound production and preferentially employed in academic studies and bioindustries. However, S.
Tian Ma +9 more
semanticscholar +2 more sources
Fermentation, 2023 Anthropogenic activities and industrial effluents are the major sources of petroleum hydrocarbon contamination in different environments. Microbe-based remediation techniques are known to be effective, inexpensive, and environmentally safe.
Nandita Das +7 more
semanticscholar +1 more source
Single cell mutant selection for metabolic engineering of actinomycetes [PDF]
, 2022 Actinomycetes are important producers of pharmaceuticals and industrial enzymes. However, wild type strains require laborious development prior to industrial usage.
Fewer David P. +7 more
core +1 more source