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Engineering Cellular Metabolism [PDF]
Cell, 2016 Metabolic engineering is the science of rewiring the metabolism of cells to enhance production of native metabolites or to endow cells with the ability to produce new products. The potential applications of such efforts are wide ranging, including the generation of fuels, chemicals, foods, feeds, and pharmaceuticals.
Nielsen, Jens, Keasling, Jay D
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Engineering yeast for high-level production of diterpenoid sclareol [PDF]
, 2023 The diterpenoid sclareol is an industrially important precursor for alternative sustainable supply of ambergris. However, its current production from plant extraction is neither economical nor environmental-friendly, since it requires laborious and cost ...
Yu, Wei, +15 more
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Metabolic engineering for the utilization of carbohydrate portions of lignocellulosic biomass.
Metabolic Engineering, 2021 The petrochemical industry has grown to meet the need for massive production of energy and commodities along with an explosive population growth; however, serious side effects such as greenhouse gas emissions and global warming have negatively impacted ...
Jiwon Kim, Sung-Hyuk Hwang, Sun-Mi Lee
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Biotechnology for Biofuels, 2021 The issues of global warming, coupled with fossil fuel depletion, have undoubtedly led to renewed interest in other sources of commercial fuels. The search for renewable fuels has motivated research into the biological degradation of lignocellulosic ...
M. Adegboye +3 more
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Considering Strain Variation and Non-Type Strains for Yeast Metabolic Engineering Applications
Life, 2022 A variety of yeast species have been considered ideal hosts for metabolic engineering to produce value-added chemicals, including the model organism Saccharomyces cerevisiae, as well as non-conventional yeasts including Yarrowia lipolytica, Kluyveromyces
Xiunan Yi, Hal S. Alper
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Metabolic Engineering of Bacteria [PDF]
Indian Journal of Microbiology, 2011 Yield and productivity are critical for the economics and viability of a bioprocess. In metabolic engineering the main objective is the increase of a target metabolite production through genetic engineering. Metabolic engineering is the practice of optimizing genetic and regulatory processes within cells to increase the production of a certain ...
Ravi R, Kumar, Satish, Prasad
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Microbial cell factories based on filamentous bacteria, yeasts, and fungi
Microbial Cell Factories, 2023 Background Advanced DNA synthesis, biosensor assembly, and genetic circuit development in synthetic biology and metabolic engineering have reinforced the application of filamentous bacteria, yeasts, and fungi as promising chassis cells for chemical ...
Qiang Ding, Chao Ye
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Metabolic engineering of Streptomyces to enhance the synthesis of valuable natural products
Engineering Microbiology, 2022 The mycelial bacterium Streptomyces is a workhorse for producing natural products, serving as a key source of drugs and other valuable chemicals. However, its complicated life cycle, silent biosynthetic gene clusters (BGCs), and poorly characterized ...
Zuwei Xu +8 more
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Metabolic Engineering of Isoflavones: An Updated Overview
Frontiers in Plant Science, 2021 Isoflavones are ecophysiologically active secondary metabolites derived from the phenylpropanoid pathway. They were mostly found in leguminous plants, especially in the pea family.
S. Sohn +5 more
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Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products [PDF]
, 2012 Zahoor ul Hassan A, Lindner S, Wendisch VF. Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products. Computational and Structural Biotechnology Journal.
Wendisch, Volker F. +8 more
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