Results 31 to 40 of about 330,730 (300)

Biosynthesis of value-added bioproducts from hemicellulose of biomass through microbial metabolic engineering

open access: yesMetabolic Engineering Communications, 2022
Hemicellulose is the second most abundant carbohydrate in lignocellulosic biomass and has extensive applications. In conventional biomass refinery, hemicellulose is easily converted to unwanted by-products in pretreatment and therefore can't be fully ...
Biao Geng   +3 more
doaj   +1 more source

Plant Metabolic Engineering [PDF]

open access: yesPlant Physiology, 2001
Metabolic engineering is generally defined as the redirection of one or more enzymatic reactions to produce new compounds in an organism, improve the production of existing compounds, or mediate the degradation of compounds.
openaire   +2 more sources

Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production

open access: yesSynthetic and Systems Biotechnology, 2020
Overproduction of polyketides has been a challenge for metabolic engineering for decades. However, recent studies have demonstrated that in both native host and heterologous host, engineering β -oxidation pathways can lead to dramatic improvement of ...
Bin Wang, Huimin Zhao
doaj   +1 more source

Protein engineering strategies for microbial production of isoprenoids

open access: yes, 2021
© 2020 The Authors Isoprenoids comprise one of the most chemically diverse family of natural products with high commercial interest. The structural diversity of isoprenoids is mainly due to the modular activity of three distinct classes of enzymes ...
Daletos, Georgios   +1 more
core   +1 more source

Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production

open access: yesMetabolites, 2015
Engineering cyanobacteria into photosynthetic microbial cell factories for the production of biochemicals and biofuels is a promising approach toward sustainability.
Martin C. Lai, Ethan I. Lan
doaj   +1 more source

Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products

open access: yes, 2012
Zahoor ul Hassan A, Lindner S, Wendisch VF. Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products. Computational and Structural Biotechnology Journal.
Wendisch, Volker F.   +8 more
core   +1 more source

Targeting riboswitches with synthetic small RNAs for metabolic engineering

open access: yes, 2021
Our growing knowledge of the diversity of non-coding RNAs in natural systems and our deepening knowledge of RNA folding and function have fomented the rational design of RNA regulators.
Picão, Bruno Willian [UNESP]   +6 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Genome-scale reconstruction and metabolic modelling of the fast-growing thermophile Geobacillus sp. LC300

open access: yes, 2022
Thermophilic microorganisms show high potential for use as biorefinery cell factories. Their high growth temperatures provide fast conversion rates, lower risk of contaminations, and facilitated purification of volatile products.
Ljungqvist, Emil E.,   +3 more
core   +1 more source

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