Results 31 to 40 of about 632,889 (322)

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

open access: yes, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

Metabolic engineering of roseoflavin-overproducing microorganisms

open access: yesMicrobial Cell Factories, 2019
Background Roseoflavin, a promising broad-spectrum antibiotic, is naturally produced by the bacteria Streptomyces davaonensis and Streptomyces cinnabarinus.
Rodrigo Mora-Lugo   +2 more
doaj   +1 more source

Biosynthesis of value-added bioproducts from hemicellulose of biomass through microbial metabolic engineering

open access: yesMetabolic Engineering Communications, 2022
Hemicellulose is the second most abundant carbohydrate in lignocellulosic biomass and has extensive applications. In conventional biomass refinery, hemicellulose is easily converted to unwanted by-products in pretreatment and therefore can't be fully ...
Biao Geng   +3 more
doaj   +1 more source

Metabolic network modularity arising from simple growth processes

open access: yes, 2012
Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering.
Takemoto, Kazuhiro
core   +1 more source

The sweet branch of metabolic engineering: cherry-picking the low-hanging sugary fruits [PDF]

open access: yes, 2015
In the first science review on the then nascent Metabolic Engineering field in 1991, Dr. James E. Bailey described how improving erythropoietin (EPO) glycosylation can be achieved via metabolic engineering of Chinese hamster ovary (CHO) cells.
Rachel Chen
core   +1 more source

Phytoestrogens [PDF]

open access: yes, 2004
Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H   +37 more
core   +1 more source

Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production

open access: yesSynthetic and Systems Biotechnology, 2020
Overproduction of polyketides has been a challenge for metabolic engineering for decades. However, recent studies have demonstrated that in both native host and heterologous host, engineering β -oxidation pathways can lead to dramatic improvement of ...
Bin Wang, Huimin Zhao
doaj   +1 more source

Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production

open access: yesMetabolites, 2015
Engineering cyanobacteria into photosynthetic microbial cell factories for the production of biochemicals and biofuels is a promising approach toward sustainability.
Martin C. Lai, Ethan I. Lan
doaj   +1 more source

(Im) Perfect robustness and adaptation of metabolic networks subject to metabolic and gene-expression regulation: marrying control engineering with metabolic control analysis [PDF]

open access: yes, 2013
Background: Metabolic control analysis (MCA) and supply–demand theory have led to appreciable understanding of the systems properties of metabolic networks that are subject exclusively to metabolic regulation.
Fromion, V., He, F., Westerhoff, H.V.
core   +10 more sources

Revealing networks from dynamics: an introduction [PDF]

open access: yes, 2014
What can we learn from the collective dynamics of a complex network about its interaction topology? Taking the perspective from nonlinear dynamics, we briefly review recent progress on how to infer structural connectivity (direct interactions) from ...
Casadiego, Jose, Timme, Marc
core   +1 more source

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