Results 31 to 40 of about 632,889 (322)
Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
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Metabolic engineering of roseoflavin-overproducing microorganisms
Background Roseoflavin, a promising broad-spectrum antibiotic, is naturally produced by the bacteria Streptomyces davaonensis and Streptomyces cinnabarinus.
Rodrigo Mora-Lugo +2 more
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Hemicellulose is the second most abundant carbohydrate in lignocellulosic biomass and has extensive applications. In conventional biomass refinery, hemicellulose is easily converted to unwanted by-products in pretreatment and therefore can't be fully ...
Biao Geng +3 more
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Metabolic network modularity arising from simple growth processes
Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering.
Takemoto, Kazuhiro
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The sweet branch of metabolic engineering: cherry-picking the low-hanging sugary fruits [PDF]
In the first science review on the then nascent Metabolic Engineering field in 1991, Dr. James E. Bailey described how improving erythropoietin (EPO) glycosylation can be achieved via metabolic engineering of Chinese hamster ovary (CHO) cells.
Rachel Chen
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Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H +37 more
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Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production
Overproduction of polyketides has been a challenge for metabolic engineering for decades. However, recent studies have demonstrated that in both native host and heterologous host, engineering β -oxidation pathways can lead to dramatic improvement of ...
Bin Wang, Huimin Zhao
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Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production
Engineering cyanobacteria into photosynthetic microbial cell factories for the production of biochemicals and biofuels is a promising approach toward sustainability.
Martin C. Lai, Ethan I. Lan
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(Im) Perfect robustness and adaptation of metabolic networks subject to metabolic and gene-expression regulation: marrying control engineering with metabolic control analysis [PDF]
Background: Metabolic control analysis (MCA) and supply–demand theory have led to appreciable understanding of the systems properties of metabolic networks that are subject exclusively to metabolic regulation.
Fromion, V., He, F., Westerhoff, H.V.
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Revealing networks from dynamics: an introduction [PDF]
What can we learn from the collective dynamics of a complex network about its interaction topology? Taking the perspective from nonlinear dynamics, we briefly review recent progress on how to infer structural connectivity (direct interactions) from ...
Casadiego, Jose, Timme, Marc
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