Results 251 to 260 of about 1,587,544 (388)

Biosynthesis of Fatty Acids by a Soluble Extract From Developing Soybean Cotyledons [PDF]

, 1969
Robert W. Rinne
openalex   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Identification and characterization of the class III peroxidase gene family in sea buckthorn (Hippophae rhamnoides subsp. sinensis Rousi) and its potential role in lignin biosynthesis. [PDF]

BMC Genomics
Zhao J, Li K, Zhao M, Jiang X, Liu X, Wang H, Sun K.   +6 more
europepmc   +1 more source

Participation of peroxisomes in lipid biosynthesis in the harderian gland of guinea pig [PDF]

, 1989
Seichi Horie, Takuya Suga
openalex   +1 more source

Biosynthesis of zinc oxide nanoparticles as a potential adsorbent for degrading organochlorines

, 2022
C.O. Ondijo, O. K’owino, F.O. Kengara
openalex   +2 more sources

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Genome-Wide Identification of Pgcyp450 Genes and Functional Analysis of the Pgcyp71be217 Gene Involved in Regulating Saponin Biosynthesis in Platycodon Grandiflorus

, 2023
Wuhua Zhang, Javed Iqbal, Zhihui Hou, Yingdong Fan, Jie Dong, Chengzhi Liu, Tao Yang, Jinzhu Zhang, Daidi Che   +8 more
openalex   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Inhibition of glycoprotein biosynthesis in the pathogenic bacterium <i>Helicobacter pylori</i> by masked carbohydrate phosphonates.

Chem Commun (Camb)
Soleimani E, Chowdhury A, Zhu JS, Ospanow E, Moulton KD, Dube DH, Jakeman DL.   +6 more
europepmc   +1 more source

MIF-expressing tumor cells mediate immunotherapeutic resistance in esophageal squamous cell carcinoma. [PDF]

Theranostics
Song J, Song X, Xie Y, Guo H, Cun Y.
europepmc   +1 more source