FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang +15 more
wiley +1 more source
Epigenetic control of the plant metabolome: implications for Chinese medicine. [PDF]
Hyun TK.
europepmc +1 more source
Dual‐emission carbon dot nanozymes are synthesized via microwave method. The nanozymes enhance photosynthesis corn seedlings through spectral‐matched light conversion. Their superoxide dismutase‐mimetic activity scavenges salt stress‐induced reactive oxygen species and circumvents energy‐intensive stress responses.
Chengfu Su +7 more
wiley +1 more source
Differential regulation of the eicosanoid biosynthesis pathway in response to Enterocytozoon hepatopenaei infection in Litopenaeus vannamei. [PDF]
Wimuttisuk W +11 more
europepmc +1 more source
Se deficiency downregulates SELENOT, disrupting mitochondrial function and elevating mtROS to induce glucose metabolic reprogramming, NADPH depletion, cysteine accumulation, and disulfidptosis‐mediated actin cytoskeleton collapse in chicken skeletal muscle.
Huanyi Liu +5 more
wiley +1 more source
Tissue-specific biosynthesis and regulation of alkaloids, flavonoids, and terpenoids in fenugreek (<i>Trigonella foenum-graecum</i> L.): insights from integrated metabolomics and transcriptomics analysis. [PDF]
Dong S, Han X, Man X, Deng X, Chen Z.
europepmc +1 more source
Integrated multi-omics identifies plant hormone signal transduction and phenylpropanoid biosynthesis as key pathways in kiwifruit (Actinidia chinensis var. deliciosa) resistance to Botryosphaeria Dothidea infection. [PDF]
Ye L +5 more
europepmc +1 more source
Living with temperature changes: Salicylic acid at the crossroads of plant immunity and temperature resilience. [PDF]
Li W +6 more
europepmc +1 more source
Transcriptomic and Metabolomic Insights into Benzylisoquinoline Alkaloid Biosynthesis in Goldthread (<i>Coptis trifolia</i>). [PDF]
Koh YS, Zhu F, Hwang Y, Yoo MJ.
europepmc +1 more source
Integrative transcriptome and metabolome evaluation of melanin biosynthesis in <i>Phyllostachys nigra</i> during low-temperature growth. [PDF]
Wang H +5 more
europepmc +1 more source

