Phenotypic and transcriptomic analysis reveals key genes associated with plant height in rubber tree and functional characterization of the candidate gene HbFLA11. [PDF]
Yang B+6 more
europepmc +1 more source
HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis
Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim+9 more
wiley +1 more source
Advances in the Biosynthesis of Plant Terpenoids: Models, Mechanisms, and Applications. [PDF]
Cheng R+5 more
europepmc +1 more source
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu+10 more
wiley +1 more source
Gut microbiome and blood biomarkers reveal differential responses to aerobic and anaerobic exercise in collegiate men of diverse training backgrounds. [PDF]
Humińska-Lisowska K+8 more
europepmc +1 more source
Hydrogen‐Producing Catalysts Based on Ferredoxin Scaffolds
Selected plant‐type ferredoxins that lack their natural [2Fe‐2S] clusters functionally bind a hydrogenase active site cofactor and act as hydrogenases themselves. In combination with photosystem I, the light‐dependent H₂ evolution almost matches the H₂ production rates of the natural system.
Yiting She+6 more
wiley +1 more source
Genome mining based on transcriptional regulatory networks uncovers a novel locus involved in desferrioxamine biosynthesis. [PDF]
Augustijn HE+7 more
europepmc +1 more source
STUDIES ON THE MECHANISM OF THE BIOSYNTHESIS OF SERINE
Chozo Mitoma, David M. Greenberg
openalex +1 more source
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo+20 more
wiley +1 more source