Results 131 to 140 of about 2,460,337 (385)

Acceptance of biotechnology and social-cultural implications in Ghana [PDF]

open access: yes
Despite major scientific progress in the application of biotechnology in agriculture, public attitudes towards biotechnology in general and genetically modified food (GM food) products in particular remain mixed in Africa.
Quaye, Wilhemina   +3 more
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Technology Vs Nature: Human Error in Dealing with Nature in Crichton\u27s Jurassic Park [PDF]

open access: yes, 2000
Witnessing the euphoria of the era of biotechnology in the late twentieth century, Crichton exposes the theme of biotechnology in his works. In Jurassic Park, he voices his concern about the impact of the use of biotechnology to preserve nature and its ...
Prasasti, S. (Sarah)   +1 more
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Innovation trends in industrial biotechnology.

open access: yesTrends in Biotechnology, 2022
J. Nielsen   +2 more
semanticscholar   +1 more source

Biotechnology for developing-country agriculture: problems and opportunities [PDF]

open access: yes
Contents: Brief 1. Overview / Gabrielle J. Persley and John J. Doyle Brief 2. Biotechnology and food and nutrition needs / Richard Flavell Brief 3. Biotechnology and animal vaccines / W. Ivan Morrison Brief 4. The role of the private sector / Clive James
Persley, Gabrielle J. (Gabrielle Josephine), ed.
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

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