Results 161 to 170 of about 2,340,402 (343)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Overview of the International Conference on Agribusiness, Environmental Engineering and Biotechnologies – AGRITECH - 2019

, 2019
И В Ковалев, A A Voroshilova, Е. А. Борисова   +2 more
openalex   +1 more source

Trends in industrial and environmental biotechnology research in Tanzania [PDF]

, 2007
Y S Mtui Godliving
openalex   +1 more source

Plant Genetic Resources for Agriculture, Plant Breeding, and Biotechnology: Experiences from Cameroon, Kenya, the Philippines, and Venezuela

, 2008
José Benjamin Falck‐Zepeda, Patricia Zambrano, Joel I. Cohen, Orángel Borges, E. P. Guimarães, Desiree M. Hautea, J. Kengue, J. M. Songa   +7 more
openalex   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Seeking a Common Path: Structuring Multistakeholder Dialogue on Agricultural Biotechnology in Africa

, 2006
Klaus von Grebmer, Steven Were Omamo
openalex   +2 more sources

Biotechnology as an Important Tool for Improving Fish Productivity [PDF]

, 2017
Isaac Adewale Omole
openalex   +1 more source

BIOREFINERIES AND BIOBASED PRODUCTS FROM THE CONSUMER'S POINT OF VIEW [PDF]

Paper prepared for presentation at the 13th ICABR International Conference on Agricultural Biotechnology: “The emerging bio-economy” Ravello (Italy), 18th to 20th June 2009Industrial biotechnology, Biorefinery, Consumer behaviour, Demand and Price ...
Kurka, Stefan, Menrad, Klaus
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source